SUMMER 2022 PUBLICATIONS » Connection Newsletter » UF Health Cancer Center

Cancer Control & Population Sciences

Burgos N, Zhao J, Brito JP, Hoang JK, Pitoia F, Maraka S, Castro MR, Lee JH (CCPS), Singh Ospina N (CCPS). Clinician agreement on the classification of thyroid nodules ultrasound features: A survey of two endocrine societies. J Clin Endocrinol Metab. 2022 May 6. pii: dgac279. doi: 10.1210/clinem/dgac279. [Epub ahead of print] PubMed PMID: 35521676.

Ilozumba MN, Yao S, Llanos AAM, Omilian AR, Zhang W (MOO), Datta S (MOO), Hong CC, Davis W, Khoury T, Bandera EV, Higgins M, Ambrosone CB. mTOR pathway gene expression in association with race and clinicopathological characteristics in Black and White breast cancer patients. Discov Oncol. 2022 May 24;13(1):34. doi: 10.1007/s12672-022-00497-y. PubMed PMID: 35608730.

Wang Y, Bian T, Song L, Jiang Y, Huo Z, Salloum RG (CCPS), Warren GW, Kaye FJ (CTHR, MOO), Fujioka N, Jin L, Xing C (CTHR). Reducing chemotherapy-induced DNA damage via nAChR-mediated redox reprograming-a new mechanism for SCLC chemoresistance boosted by nicotine. Cancers (Basel). 2022 May 2;14(9). pii: 2272. doi: 10.3390/cancers14092272. PubMed PMID: 35565402; PubMed Central PMCID: PMC9100082.

Yaghjyan L (CCPS), McLaughlin E, Lehman A, Neuhouser ML, Rohan T, Lane DS, Snetselaar L, Paskett E. Associations of coffee/caffeine consumption with postmenopausal breast cancer risk and their interactions with postmenopausal hormone use. Eur J Nutr. 2022 May 18. doi: 10.1007/s00394-022-02899-8. [Epub ahead of print] PubMed PMID: 35583696.

Phelan R, Im A, Hunter RL, Inamoto Y, Lupo-Stanghellini MT, Rovo A, Badawy SM, Burns L, Eissa H, Murthy HS, Prasad P, Sharma A, Suelzer E, Agrawal V, Aljurf M, Baker K, Basak GW, Buchbinder D, DeFilipp Z, Grkovic LD, Dias A, Einsele H, Eisenberg ML, Epperla N, Farhadfar N (CCPS), Flatau A, Gale RP, Greinix H, Hamilton BK, Hashmi S, Hematti P, Jamani K, Maharaj D, Murray J, Naik S, Nathan S, Pavletic S, Peric Z, Pulanic D, Ross R, Salonia A, Sanchez-Ortega I, Savani BN, Schechter T, Shah AJ, Smith SM, Snowden JA, Steinberg A, Tremblay D, Vij SC, Walker L, Wolff D, Yared JA, Schoemans H, Tichelli A. Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Bone Marrow Transplant. 2022 May 6. doi: 10.1038/s41409-022-01591-z. [Epub ahead of print] PubMed PMID: 35523848.

Bruijnzeel AW (CCPS). The unhealthy association between smoking, vaping, and other drug use. Nicotine Tob Res. 2022 May 18. pii: ntac130. doi: 10.1093/ntr/ntac130. [Epub ahead of print] PubMed PMID: 35584805.

Cassidy V, Amdur RJ (CCPS). Esophageal damage from thoracic spine stereotactic body radiation therapy. Pract Radiat Oncol. 2022 May 2. pii: S1879-8500(22)00136-9. doi: 10.1016/j.prro.2022.04.007. [Epub ahead of print] PubMed PMID: 35513255.

Moosvi K, Schoppee TM, Xavier S, Henderson K, Suarez ML, Yao Y (CCPS), Wilkie DJ (CCPS). Feasibility and burden of lay caregivers providing daily massages to patients with cancer receiving hospice and palliative care. Am J Hosp Palliat Care. 2022 May 25:10499091221105881. doi: 10.1177/10499091221105881. [Epub ahead of print] PubMed PMID: 35613662.

Lyon D (CCPS). Responding to pandemic-associated changes in cancer prevention and screening. Oncol Nurs Forum. 2022 May 1;49(3):189-190. doi: 10.1188/22.ONF.189-190. PubMed PMID: 35446831.

Canzona MR, Fisher CL (CCPS), Garcia DS, Dong T, Ledford CJW. Partner presence in clinical conversations about sexual health: Breast cancer survivors’, partners’, and providers’ perspectives of triadic interactions. J Psychosoc Oncol. 2022 May 19:1-16. doi: 10.1080/07347332.2022.2068397. [Epub ahead of print] PubMed PMID: 35587166.

Smith JD, Mandel G, Niazi T, Bradley JA (CCPS), Indelicato DJ (CTHR), Khatib Z. Multifocal and multiphasic demyelinating lesions after radiation for ependymoma in a pediatric population. J Child Neurol. 2022 May 26:8830738221079476. doi: 10.1177/08830738221079476. [Epub ahead of print] PubMed PMID: 35619552.

Zhang D, Leeuwenburgh C, Zhou D, Gong Y (CCPS), Pahor M, Licht JD (MOO), Braithwaite D (CCPS). Analysis of biological aging and risks of all-cause and cardiovascular disease-specific death in cancer survivors. JAMA Netw Open. 2022 Jun 1;5(6):e2218183. doi: 10.1001/jamanetworkopen.2022.18183. PubMed PMID: 35731518.

Paige SR, Campbell-Salome G, Alpert J (CCPS), Markham MJ (CTHR), Murphy M (CCPS), Heffron E, Harle C, Yue S, Xue W, Bylund CL (CCPS). Cancer patients’ satisfaction with telehealth during the COVID-19 pandemic. PLoS One. 2022 Jun 3;17(6):e0268913. doi: 10.1371/journal.pone.0268913. eCollection 2022. PubMed PMID: 35657778.

Farhadfar N (CCPS), Ahn KW, Bo-Subait S, Logan B, Stefanski H, Hsu JW (CTHR), Panch S, Confer D, Liu H, Badawy SM, Beitinjaneh A, Diaz MA, Hildebrandt GC, Kelkar AH, Lazarus HM, Murthy H, Preussler JM, Schears RM, Sharma A, van der Poel M, Bruce JG, Pulsipher MA, Shaw BE, Wingard JR (CTHR), Switzer GE. The impact of pre-apheresis health related quality of life on peripheral blood progenitor cell yield and donor’s health and outcome: Secondary analysis of Patient-Reported Outcome Data from the RDSafe and BMT CTN 0201 Clinical Trials. Transplant Cell Ther. 2022 Jun 7. pii: S2666-6367(22)01361-6. doi: 10.1016/j.jtct.2022.05.042. [Epub ahead of print] PubMed PMID: 35688325.

Herremans KM, Szymkiewicz DD, Riner AN, Bohan RP, Tushoski GW, Davidson AM, Lou X (CCPS), Leong MC, Dean BD, Gerber M, Underwood PW, Han S, Hughes SJ (CTHR). The interleukin-1 axis and the tumor immune microenvironment in pancreatic ductal adenocarcinoma. Neoplasia. 2022 Jun;28:100789. doi: 10.1016/j.neo.2022.100789. Epub 2022 Apr 5. PubMed PMID: 35395492; PubMed Central PMCID: PMC8990176.

Burgos N, Ospina NS (CCPS), Sipos JA. The future of thyroid nodule risk stratification. Endocrinol Metab Clin North Am. 2022 Jun;51(2):305-321. doi: 10.1016/j.ecl.2021.12.002. Epub 2022 May 4. Review. PubMed PMID: 35662443.

Fabregas JC (CCPS), Ramnaraign B (CTHR), George TJ (CTHR). Clinical updates for colon cancer care in 2022. Clin Colorectal Cancer. 2022 Jun 3. pii: S1533-0028(22)00067-6. doi: 10.1016/j.clcc.2022.05.006. [Epub ahead of print] Review. PubMed PMID: 35729033.

Barreto IL, Grajo JR, Brock DE, Magnelli L, Patel P, Hochhegger B (CCPS). A health system’s response to the ongoing global shortage of iodinated contrast media. AJR Am J Roentgenol. 2022 Jun 22. doi: 10.2214/AJR.22.28060. [Epub ahead of print] PubMed PMID: 35731094.

Normando AGC, Pérez-de-Oliveira ME, Guerra ENS, Lopes MA, Rocha AC, Brandão TB, Prado-Ribeiro AC, Gueiros LAM, Epstein JB, Migliorati CA (CCPS), Santos-Silva AR; Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). To extract or not extract teeth prior to head and neck radiotherapy? A systematic review and meta-analysis. Support Care Cancer. 2022 Jun 17. doi: 10.1007/s00520-022-07215-y. [Epub ahead of print] Review. PubMed PMID: 35713725.

Braithwaite D (CCPS), Karanth SD, Slatore CG, Zhang D, Bian J (CCPS), Meza R, Jeon J, Tammemagi M, Schabath M, Wheeler M, Guo Y (CCPS), Hochhegger B (CCPS), Kaye FJ (CTHR, MOO), Silvestri GA, Gould MK. Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational study. BMJ Open. 2022 Jun 22;12(6):e064142. doi: 10.1136/bmjopen-2022-064142. PubMed PMID: 35732383.

Bylund CL (CCPS), Taylor G, Mroz E, Wilkie DJ (CCPS), Yao Y (CCPS), Emanuel L, Fitchett G, Handzo G, Chochinov HM, Bluck S (CCPS). Empathic communication in dignity therapy: Feasibility of measurement and descriptive findings. Palliat Support Care. 2022 Jun;20(3):321-327. doi: 10.1017/S1478951521001188. PubMed PMID: 35713352.

de Mattos JN, Santiago Escovar CE, Zereu M, Rubin AS, Camargo SM, Mohammed TL, Dos Santos RS, Verma N, Penha Pereira D, Guedes Pinto E, Machuca T, Medeiros TM, Hochhegger B (CCPS). Computed tomography on lung cancer screening is useful for adjuvant comorbidity diagnosis in developing countries. ERJ Open Res. 2022 Jun 20;8(2). pii: 00061-2022. doi: 10.1183/23120541.00061-2022. eCollection 2022 Apr. PubMed PMID: 35747230; PubMed Central PMCID: PMC9209849.

Cancer Therapeutics & Host Response

Law ME, Yaaghubi E, Ghilardi AF, Davis BJ, Ferreira RB, Koh J, Chen S, DePeter SF, Schilson CM, Chiang CW, Heldermon CD (CTHR), NÃ¸rgaard P, Castellano RK (CTHR), Law BK (CTHR). Inhibitors of ERp44, PDIA1, and AGR2 induce disulfide-mediated oligomerization of Death Receptors 4 and 5 and cancer cell death. Cancer Lett. 2022 May 28;534:215604. doi: 10.1016/j.canlet.2022.215604. Epub 2022 Mar 2. PubMed PMID: 35247515.

Shalabi H, Qin H, Su A, Yates B, Wolters PL, Steinberg SM, Ligon JA (CTHR), Silbert S, DÃ©DÃ© K, Benzaoui M, Goldberg SY, Achar S, Schneider D, Shahani SA, Little L, Foley T, Molina JC, Panch S, Mackall CL, Lee DW, Chien CD, Pouzolles M, Ahlman MA, Yuan CM, Wang HW, Wang Y, Inglefield J, Tamula MA, Martin S, Highfill SL, Altan-Bonnet G, Stroncek DF, Fry TJ, Taylor N, Shah NN. CD19/22 CAR T-cells in children and young adults with B-ALL: Phase I results and development of a novel bicistronic CAR. Blood. 2022 May 23. pii: blood.2022015795. doi: 10.1182/blood.2022015795. [Epub ahead of print] PubMed PMID: 35605184.

Thanarajasingam G, Minasian LM, Bhatnagar V, Cavalli F, De Claro RA, Dueck AC, El-Galaly TC, Everest N, Geissler J, Gisselbrecht C, Gormley N, Gribben J, Horowitz M, Ivy SP, Jacobson CA, Keating A, Kluetz PG, Kwong YL, Little RF, Matasar MJ, Mateos MV, McCullough K, Miller RS, Mohty M, Moreau P, Morton LM, Nagai S, Nair A, Nastoupil L, Robertson K, Sidana S, Smedby KE, Sonneveld P, Tzogani K, van Leeuwen FE, Velikova G, Villa D, Wingard JR (CTHR), Seymour JF, Habermann TM. Reaching beyond maximum grade: progress and future directions for modernising the assessment and reporting of adverse events in haematological malignancies. Lancet Haematol. 2022 May;9(5):e374-e384. doi: 10.1016/S2352-3026(22)00045-X. Review. PubMed PMID: 35483398.

Rodwin RL, Kairalla JA (CTHR), Hibbitts E, Devidas M, Whitley MK, Mohrmann CE, Schore RJ, Raetz E, Winick NJ, Hunger SP, Loh ML, Hockenberry MJ, Angiolillo AL, Ness KK, Kadan-Lottick NS. Persistence of chemotherapy-induced peripheral neuropathy despite vincristine reduction in childhood b-acute lymphoblastic leukemia. J Natl Cancer Inst. 2022 May 12. pii: djac095. doi: 10.1093/jnci/djac095. [Epub ahead of print] PubMed PMID: 35552709.

Dominguez-Gutierrez PR, Kwenda EP, Donelan W (CTHR), Miranda M, Doty A, O’Malley P (CTHR), Crispen PL (CTHR), Kusmartsev S (CTHR). Detection of PD-L1-expressing myeloid cell clusters in the hyaluronan-enriched stroma in tumor tissue and tumor-draining lymph nodes. J Immunol. 2022 May 18. pii: ji2100026. doi: 10.4049/jimmunol.2100026. [Epub ahead of print] PubMed PMID: 35589125.

Montalvo R, Boeno FP, Ozdemir M, Dowllah IM, Doerr V, Bomkamp MP, Nguyen BL, Smuder AJ (CTHR). Response of subsarcolemmal and intermyofibrillar mitochondria to exercise and doxorubicin-induced cardiotoxicity. FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.0R833. PubMed PMID: 35553397.

Taner T, Bruner J, Emamaullee J, Bonaccorsi-Riani E, Zarrinpar A (CTHR). New approaches to the diagnosis of rejection and prediction of tolerance in liver transplantation. Transplantation. 2022 May 16. doi: 10.1097/TP.0000000000004160. [Epub ahead of print] PubMed PMID: 35594482.

Hitchcock KE (CTHR), Romesser PB, Miller ED. Local therapies in advanced colorectal cancer. Hematol Oncol Clin North Am. 2022 May 10. pii: S0889-8588(22)00007-7. doi: 10.1016/j.hoc.2022.02.007. [Epub ahead of print] Review. PubMed PMID: 35562258.

Ghilardi AF, Yaaghubi E, Ferreira RB, Law ME, Yang Y, Davis BJ, Schilson CM, Ghiviriga I, Roitberg AE, Law BK (CTHR), Castellano RK (CTHR). Anticancer agents derived from cyclic thiosulfonates: structure-reactivity and structure-activity relationships. ChemMedChem. 2022 May 1:e202200165. doi: 10.1002/cmdc.202200165. [Epub ahead of print] PubMed PMID: 35491396.

Gonsalves C, Ross J, Esnakula A, Leon M (CTHR). Metastatic high-grade endometrial stromal sarcoma with BCOR translocation to the pleural fluid: a case report. Int J Surg Pathol. 2022 May 16:10668969221098093. doi: 10.1177/10668969221098093. [Epub ahead of print] PubMed PMID: 35570590.

McBride A, Hudson-DiSalle S, Pilz J, Hamm M, Boring B, Buie LW, DeRemer DL (CTHR). National survey on the effect of oncology drug shortages in clinical practice: A Hematology Oncology Pharmacy Association survey. JCO Oncol Pract. 2022 May 11:OP2100883. doi: 10.1200/OP.21.00883. [Epub ahead of print] PubMed PMID: 35544740.

Nguyen DT, Ogando-Rivas E, Liu R, Wang T, Rubin J, Jin L, Tao H, Sawyer WW, Mendez-Gomez HR, Cascio M (CTHR), Mitchell DA (CTHR), Huang J (CTHR), Sawyer WG (CTHR), Sayour EJ (CTHR), Castillo P (CTHR). CAR T cell locomotion in solid tumor microenvironment. Cells. 2022 Jun 20;11(12). pii: 1974. doi: 10.3390/cells11121974. Review. PubMed PMID: 35741103.

Wu Q, O’Malley J, Datta S (MOO), Gharaibeh RZ (CTHR), Jobin C (CTHR), Karagas MR, Coker MO, Hoen AG, Christensen BC, Madan JC, Li Z (CTHR). MarZIC: A marginal mediation model for zero-inflated compositional mediators with applications to microbiome data. Genes (Basel). 2022 Jun 11;13(6). pii: 1049. doi: 10.3390/genes13061049. PubMed PMID: 35741811.

Drewes JL, Chen J, Markham NO, Knippel RJ, Domingue JC, Tam AJ, Chan JL, Kim L, McMann M, Stevens C, Dejea CM, Tomkovich S, Michel J, White JR, Mohammad F, Campodonico VL, Heiser CN, Wu X, Wu S, Ding H, Simner P, Carroll K, Shrubsole MJ, Anders RA, Walk ST, Jobin C (CTHR), Wan F, Coffey RJ, Housseau F, Lau KS, Sears CL. Human colon cancer-derived Clostridioides difficile strains drive colonic tumorigenesis in mice. Cancer Discov. 2022 Jun 9. pii: candisc.1273.2021-10-4 15:58:09.930. doi: 10.1158/2159-8290.CD-21-1273. [Epub ahead of print] PubMed PMID: 35678528.

Herremans KM, Riner AN, Cameron ME, McKinley KL, Triplett EW, Hughes SJ (CTHR), Trevino JG. The oral microbiome, pancreatic cancer and human diversity in the age of precision medicine. Microbiome. 2022 Jun 15;10(1):93. doi: 10.1186/s40168-022-01262-7. Review. PubMed PMID: 35701831.

Gbadamosi MO, Shastri VM, Elsayed AH, Ries R, Olabige O, Nguyen NHK, De Jesus A, Wang YC, Dang A, Hirsch BA, Alonzo TA, Gamis A, Meshinchi S, Lamba JK (CTHR). A ten-gene DNA-damage response pathway gene expression signature predicts gemtuzumab ozogamicin response in pediatric AML patients treated on COGAAML0531 and AAML03P1 trials. Leukemia. 2022 Jun 10. doi: 10.1038/s41375-022-01622-0. [Epub ahead of print] PubMed PMID: 35688939.

Akulian J, Bedawi EO, Abbas H, Argento C, Arnold DT, Balwan A, Batra H, Uribe Becerra JP, Belanger A, Berger K, Burks AC, Chang J, Chrissian AA, DiBardino DM, Fuentes XF, Gesthalter YB, Gilbert CR, Glisinski K, Godfrey M, Gorden JA, Grosu H, Gupta M, Kheir F, Ma KC, Majid A, Maldonado F, Maskell NA, Mehta H (CTHR), Mercer J, Mullon J, Nelson D, Nguyen E, Pickering EM, Puchalski J, Reddy C, Revelo AE, Roller L, Sachdeva A, Sanchez T, Sathyanarayan P, Semaan R, Senitko M, Shojaee S, Story R, Thiboutot J, Wahidi M, Wilshire CL, Yu D, Zouk A, Rahman NM, Yarmus L; Interventional Pulmonary Outcomes Group (IPOG). Bleeding risk with combination intrapleural fibrinolytic and enzyme therapy in pleural infection – an international, multicenter, retrospective cohort study. Chest. 2022 Jun 15. pii: S0012-3692(22)01089-3. doi: 10.1016/j.chest.2022.06.008. [Epub ahead of print] PubMed PMID: 35716828.

AlMasri S, Zenati M, Hammad A, Nassour I (CTHR), Liu H, Hogg ME, Zeh HJ, Boone B, Bahary N, Singhi AD, Lee KK, Paniccia A, Zureikat AH. Adaptive dynamic therapy and survivorship for operable pancreatic cancer. JAMA Netw Open. 2022 Jun 1;5(6):e2218355. doi: 10.1001/jamanetworkopen.2022.18355. PubMed PMID: 35737385.

Deyhle MR, Callaway CS, Neyroud D, D’Lugos AC, Judge SM, Judge AR (CTHR). Depleting Ly6G positive myeloid cells reduces pancreatic cancer-induced skeletal muscle atrophy. Cells. 2022 Jun 10;11(12). pii: 1893. doi: 10.3390/cells11121893. PubMed PMID: 35741022.

Busaidy N, Konda B, Wei L, Wirth LJ, Devine C, Daniels GA, DeSouza JA, Poi M, Seligson ND (CTHR), Cabanillas M, Sipos JA, Ringel MD, Eisfeld AK, Timmers C, Shah MH MD. Dabrafenib vs dabrafenib + trametinib in BRAF-mutated radioactive iodine refractory differentiated thyroid cancer – results of a randomized, phase 2, open-label, multicenter trial. Thyroid. 2022 Jun 4. doi: 10.1089/thy.2022.0115. [Epub ahead of print] PubMed PMID: 35658604.

Farhadfar N (CCPS), Ahn KW, Bo-Subait S, Logan B, Stefanski H, Hsu JW (CTHR), Panch S, Confer D, Liu H, Badawy SM, Beitinjaneh A, Diaz MA, Hildebrandt GC, Kelkar AH, Lazarus HM, Murthy H, Preussler JM, Schears RM, Sharma A, van der Poel M, Bruce JG, Pulsipher MA, Shaw BE, Wingard JR (CTHR), Switzer GE. The impact of pre-apheresis health related quality of life on peripheral blood progenitor cell yield and donor’s health and outcome: Secondary analysis of patient-reported outcome data from the RDSafe and BMT CTN 0201 clinical trials. Transplant Cell Ther. 2022 Jun 7. pii: S2666-6367(22)01361-6. doi: 10.1016/j.jtct.2022.05.042. [Epub ahead of print] PubMed PMID: 35688325.

Ligon JA (CTHR), Fry A, Maher JY, Foley T, Silbert S, Yates B, Gomez-Lobo V, Wiener L, Shah NN. Fertility and CAR T-cells: Current practice and future directions. Transplant Cell Ther. 2022 Jun 12. pii: S2666-6367(22)01363-X. doi: 10.1016/j.jtct.2022.06.002. [Epub ahead of print] PubMed PMID: 35705177.

Gao T, Lott AA, Huang F, Rohokale R, Li Q, Olivos HJ, Chen S, Guo Z (CTHR). Structural characterization and analysis of different epimers of neutral glycosphingolipid LcGg4 by ion mobility spectrometry-mass spectrometry. Analyst. 2022 Jun 13. doi: 10.1039/d2an00224h. [Epub ahead of print] PubMed PMID: 35695136.

Prisciandaro J, Zoberi JE, Cohen G, Kim Y, Johnson P (CTHR), Paulson E, Song W, Hwang KP, Erickson B, Beriwal S, Kirisits C, Mourtada F. AAPM task group report 303 endorsed by the ABS: MRI implementation in HDR brachytherapy-Considerations from simulation to treatment. Med Phys. 2022 Jun 3. doi: 10.1002/mp.15713. [Epub ahead of print] PubMed PMID: 35662032.

Suárez C, López F, Rodrigo JP, Mendenhall WM (CTHR), de Bree R, Mäkitie AA, Vander Poorten V, Takes RP, Bondi S, Kowalski LP, Shaha AR, Fernández-Alvarez V, Gutiérrez JC, Zidar N, Chiesa-Estomba C, Strojan P, Sanabria A, Rinaldo A, Ferlito A. Benign peripheral non-cranial nerve sheath tumors of the neck. Adv Ther. 2022 Jun 11. doi: 10.1007/s12325-022-02191-5. [Epub ahead of print] Review. PubMed PMID: 35689724.

Braithwaite D (CCPS), Karanth SD, Slatore CG, Zhang D, Bian J (CCPS), Meza R, Jeon J, Tammemagi M, Schabath M, Wheeler M, Guo Y (CCPS), Hochhegger B (CCPS), Kaye FJ (CTHR, MOO), Silvestri GA, Gould MK. Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre observational study. BMJ Open. 2022 Jun 22;12(6):e064142. doi: 10.1136/bmjopen-2022-064142. PubMed PMID: 35732383.

Narla ST, Rice L (CTHR), Ostrov D (CTHR), Bushnell DS, Duara JL, Bates CM. Durability of and role of AKT in FGF7p urothelial protection against cyclophosphamide. Physiol Rep. 2022 Jun;10(12):e15358. doi: 10.14814/phy2.15358. PubMed PMID: 35748317.

Mechanisms of Oncogenesis

Combs LR, Spires LM, Alonso JD, Papp B (MOO), Toth Z (MOO). KSHV RTA induces degradation of the host transcription repressor ID2 to promote the viral lytic cycle. J Virol. 2022 May 23:e0010122. doi: 10.1128/jvi.00101-22. [Epub ahead of print] PubMed PMID: 35604218.

Pillai S, Mahmud I, Mahar R, Griffith C, Langsen M, Nguyen J, Wojtkowiak JW, Swietach P, Gatenby RA, Bui MM, Merritt ME, McDonald P, Garrett TJ (MOO), Gillies RJ. Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy. Cell Rep. 2022 May 10;39(6):110796. doi: 10.1016/j.celrep.2022.110796. PubMed PMID: 35545051.

Wang Y, Bian T, Song L, Jiang Y, Huo Z, Salloum RG (CCPS), Warren GW, Kaye FJ (CTHR, MOO), Fujioka N, Jin L, Xing C (CTHR). Reducing chemotherapy-induced DNA damage via nAChR-mediated redox reprograming-A new mechanism for SCLC chemoresistance boosted by nicotine. Cancers (Basel). 2022 May 2;14(9). pii: 2272. doi: 10.3390/cancers14092272. PubMed PMID: 35565402; PubMed Central PMCID: PMC9100082.

Fernández-Rodríguez J, Creus-Bachiller E, Zhang X, Martínez-Iniesta M, Ortega-Bertran S, Guha R, Thomas CJ, Wallace MR (MOO), Romagosa C, Salazar-Huayna L, Reilly KM, Blakely JO, Serra-Musach J, Pujana MA, Serra E, Villanueva A, Ferrer M, Lázaro C. A high-throughput screening platform identifies novel combination treatments for malignant peripheral nerve sheath tumors. Mol Cancer Ther. 2022 May 5. pii: molcanther.MCT-21-0947-A.2021. doi: 10.1158/1535-7163.MCT-21-0947. [Epub ahead of print] PubMed PMID: 35511749.

Ilozumba MN, Yao S, Llanos AAM, Omilian AR, Zhang W (MOO), Datta S (MOO), Hong CC, Davis W, Khoury T, Bandera EV, Higgins M, Ambrosone CB, Cheng TD. mTOR pathway gene expression in association with race and clinicopathological characteristics in Black and White breast cancer patients. Discov Oncol. 2022 May 24;13(1):34. doi: 10.1007/s12672-022-00497-y. PubMed PMID: 35608730.

Wang Y, Ungerleider N, Hoffman BA, Kara M, Farrell PJ, Flemington EK, Lee N, Tibbetts SA (MOO). A polymorphism in the Epstein-Barr virus EBER2 noncoding RNA drives In vivo expansion of latently infected B cells. mBio. 2022 Jun 1:e0083622. doi: 10.1128/mbio.00836-22. [Epub ahead of print] PubMed PMID: 35642944.

Gobin CM, Menefee JN, Lattimore CC, Doty A, Fredenburg KM (MOO). Cell dissociation enzymes affect Annexin V/Flow-Cytometric Apoptotic Assay outcomes after miRNA-based transient transfection. Anticancer Res. 2022 Jun;42(6):2819-2825. doi: 10.21873/anticanres.15763. PubMed PMID: 35641293.

Li Z, Ji BW, Dixit PD (MOO), Tchourine K, Lien EC, Hosios AM, Abbott KL, Rutter JC, Westermark AM, Gorodetsky EF, Sullivan LB, Vander Heiden MG, Vitkup D. Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Nat Metab. 2022 Jun 23. doi: 10.1038/s42255-022-00588-8. [Epub ahead of print] PubMed PMID: 35739397.

Brégeon D, Pecqueur L, Toubdji S, Sudol C, Lombard M, Fontecave M, de Crécy-Lagard V (MOO), Motorin Y, Helm M, Hamdane D. Dihydrouridine in the transcriptome: new life for this ancient RNA chemical modification. ACS Chem Biol. 2022 Jun 23. doi: 10.1021/acschembio.2c00307. [Epub ahead of print] Review. PubMed PMID: 35737906.