SEPTEMBER 2022 PUBLICATIONS

Cancer Control & Population Sciences

Cancer Therapeutics & Host Response

Mechanisms of Oncogenesis


Cancer Control & Population Sciences

Mailhot Vega RB, Wang S, Brooks ED, Oladeru OT, Lockney NA, Spiguel LE, MacDonald SM, Mamounas EP, Mendenhall NP, Okunieff PG, Lee JH, Bradley JA. Evaluating regional nodal irradiation allocation and association with oncologic outcomes in NSABP B-18, B-27, B-40, and B-41. Int J Radiat Oncol Biol Phys. 2022 Jul 1;113(3):542-551. doi: 10.1016/j.ijrobp.2022.03.007. Epub 2022 Mar 29. PubMed PMID: 35418342; PubMed Central PMCID: PMC9250597.

Chen Z, Zhang H, George TJ, Guo Y, Prosperi M, Guo J, Braithwaite D, Wang F, Kibbe W, Wagner L, Bian J. Simulating colorectal cancer trials using real-world data. JCO Clin Cancer Inform. 2022 Jul;6:e2100195. doi: 10.1200/CCI.21.00195. PubMed PMID: 35839432.

Bylund CL, Wollney EN, Campbell-Salome G, Applebaum AJ, Paige SR, DeGruccio K, Weiss E, Sae-Hau M, Arnold J, Durante D, Amin TB, Hampton CN, Fisher CL. Improving clinical and family communication for adult child caregivers of a parent with a blood cancer: single-arm pre-post pilot intervention. JMIR Cancer. 2022 Jul 5;8(3):e38722. doi: 10.2196/38722. PubMed PMID: 35788019; PubMed Central PMCID: PMC9297135.

DeZern AE, Eapen M, Wu J, Talano JA, Solh M, Dávila Saldaña BJ, Karanes C, Horwitz ME, Mallhi K, Arai S, Farhadfar N, Hexner E, Westervelt P, Antin JH, Deeg HJ, Leifer E, Brodsky RA, Logan BR, Horowitz MM, Jones RJ, Pulsipher MA. Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase 2 trial. Lancet Haematol. 2022 Jul 27. pii: S2352-3026(22)00206-X. doi: 10.1016/S2352-3026(22)00206-X. [Epub ahead of print] PubMed PMID: 35907408.

Knight JM, Taylor MR, Rentscher KE, Henley EC, Uttley HA, Nelson AM, Turcotte LM, McAndrew NS, Amonoo HL, Mohanraj L, Kelly DL, Costanzo ES. Biobehavioral implications of Covid-19 for transplantation and cellular therapy recipients. Front Immunol. 2022 Jul 5;13:877558. doi: 10.3389/fimmu.2022.877558. eCollection 2022. Review. PubMed PMID: 35865530; PubMed Central PMCID: PMC9295749.

Bian T, Wang Y, Botello JF, Hu Q, Jiang Y, Zingone A, Ding H, Wu Y, Zahra Aly F, Salloum RG, Warren G, Huo Z, Ryan BM, Jin L, Xing C. LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner. Oncogene. 2022 Jul 14. doi: 10.1038/s41388-022-02410-x. [Epub ahead of print] PubMed PMID: 35835853.

Thomas CD, Franchi F, Keeley EC, Rossi JS, Winget M, David Anderson R, Dempsey AL, Gong Y, Gower MN, Kerensky RA, Kulick N, Malave JG, McDonough CW, Mulrenin IR, Starostik P, Beitelshees AL, Johnson JA, Stouffer GA, Winterstein AG, Angiolillo DJ, Lee CR, Cavallari LH. Impact of the ABCD-GENE score on clopidogrel clinical effectiveness after PCI: A multi-site, real-world investigation. Clin Pharmacol Ther. 2022 Jul;112(1):146-155. doi: 10.1002/cpt.2612. Epub 2022 May 2. PubMed PMID: 35429163; PubMed Central PMCID: PMC9233085.

Hammond MM, Spring B, Rejeski WJ, Sufit R, Criqui MH, Tian L, Zhao L, Xu S, Kibbe MR, Leeuwenburgh C, Manini T, Forman DE, Treat-Jacobson D, Polonsky TS, Bazzano L, Ferrucci L, Guralnik J, Lloyd-Jones DM, McDermott MM. Effects of walking exercise at a pace with versus without ischemic leg symptoms on functional performance measures in people with lower extremity peripheral artery disease: The LITE Randomized Clinical Trial. J Am Heart Assoc. 2022 Jul 27:e025063. doi: 10.1161/JAHA.121.025063. [Epub ahead of print] PubMed PMID: 35894088.

Hong YR, Xie Z, Yadav S, Tanner R, Striley C, Marlow NM. Opioid use behaviors among people with disability in the United States: An analysis of the National Survey on Drug Use and Health. J Addict Med. 2022 Jul 21. doi: 10.1097/ADM.0000000000001031. [Epub ahead of print] PubMed PMID: 35861360.

Hicklin K, O’Leary MC, Nambiar S, Mayorga ME, Wheeler SB, Davis MM, Richardson LC, Tangka FKL, Lich KH. Assessing the impact of multicomponent interventions on colorectal cancer screening through simulation: What would it take to reach national screening targets in North Carolina? Prev Med. 2022 Jul 3;162:107126. doi: 10.1016/j.ypmed.2022.107126. [Epub ahead of print] PubMed PMID: 35787844.

Bouchard EG, Collins RL, Vincent PC, Patel H, Sahler OJZ, McCarty C, Prince MA, Kelly KM. An initial investigation of using smartphone-enabled micro-temporal data collection to increase acceptability, feasibility, and validity of research on cancer caregiving. Pediatr Blood Cancer. 2022 Jul 23:e29886. doi: 10.1002/pbc.29886. [Epub ahead of print] PubMed PMID: 35869890.

Odeh R, Diehl ERM, Nixon SJ, Tisher CC, Klempner D, Sonke JK, Colquhoun TA, Li Q, Espinosa M, Perdomo D, Rosario K, Terzi H, Guy CL. A pilot randomized controlled trial of group-based indoor gardening and art activities demonstrates therapeutic benefits to healthy women. PLoS One. 2022 Jul 6;17(7):e0269248. doi: 10.1371/journal.pone.0269248. eCollection 2022. PubMed PMID: 35793277; PubMed Central PMCID: PMC9258874.

Awawda S, Chalak A, Khader Y, Mostafa A, Abla R, Nakkash R, Jawad M, Salloum RG, Abu-Rmeileh NM. Gender differences in the price elasticity of demand for waterpipe and cigarette smoking in Lebanon, Jordan and Palestine: a volumetric choice experiment. BMJ Open. 2022 Jul 18;12(7):e058495. doi: 10.1136/bmjopen-2021-058495. PubMed PMID: 35851023.

Tirkes T, Dasyam AK, Shah ZK, Fogel EL, Vege SS, Li L, Li S, Chang ST, Farinas CA, Grajo JR, Mawad K, Takahashi N, Venkatesh SK, Wachsman A, Fisher WE, Forsmark CE, Hart PA, Pandol SJ, Park WG, Van Den Eeden SK, Yang Y, Topazian M, Andersen DK, Serrano J, Conwell DL, Yadav D; Consortium for the Study of Chronic Pancreatitis, Diabetes, Pancreatic Cancer (CPDPC). T1 signal intensity ratio of the pancreas as an imaging biomarker for the staging of chronic pancreatitis. Abdom Radiol (NY). 2022 Jul 20. doi: 10.1007/s00261-022-03611-4. [Epub ahead of print] PubMed PMID: 35857066.

Mobley EM, Thomas SM, Brailsford J, Ochoa CY, Miller K, Applebaum A, Milam J, Freyer DR. Clinical trial participation: A qualitative study of adolescents and younger adults recently diagnosed with cancer. J Adolesc Young Adult Oncol. 2022 Jul 27. doi: 10.1089/jayao.2022.0050. [Epub ahead of print] PubMed PMID: 35900287.

Ekwueme DU, Halpern MT, Chesson HW, Ashok M, Drope J, Hong YR, Maciosek M, Pesko MF, Kenkel DS. Health economics research in primary prevention of cancer: assessment, current challenges, and future directions. J Natl Cancer Inst Monogr. 2022 Jul 5;2022(59):28-41. doi: 10.1093/jncimonographs/lgac014. Review. PubMed PMID: 35788376.

Lee CJ, Wang T, Chen K, Arora M, Brazauskas R, Spellman SR, Kitko C, MacMillan ML, Pidala JA, Auletta JJ, Badawy SM, Bhatt N, Bhatt VR, Cahn JY, DeFilipp Z, Diaz MA, Farhadfar N, Gadalla S, Gale RP, Hashem H, Hashmi S, Hematti P, Hong S, Hossain NM, Inamoto Y, Lekakis LJ, Modi D, Patel S, Sharma A, Solomon S, Couriel DR. Association of chronic graft-versus-host disease with late effects following allogeneic hematopoietic cell transplantation for children with hematologic malignancy. Transplant Cell Ther. 2022 Jul 18. pii: S2666-6367(22)01475-0. doi: 10.1016/j.jtct.2022.07.014. [Epub ahead of print] PubMed PMID: 35863740.


Cancer Therapeutics & Host Response

Bian T, Wang Y, Botello JF, Hu Q, Jiang Y, Zingone A, Ding H, Wu Y, Zahra Aly F, Salloum RG, Warren G, Huo Z, Ryan BM, Jin L, Xing C. LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner. Oncogene. 2022 Jul 14. doi: 10.1038/s41388-022-02410-x. [Epub ahead of print] PubMed PMID: 35835853.

He N, Thippabhotla S, Zhong C, Greenberg Z, Xu L, Pessetto Z, Godwin AK, Zeng Y, He M. Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection. Commun Biol. 2022 Jul 4;5(1):660. doi: 10.1038/s42003-022-03598-0. PubMed PMID: 35787656; PubMed Central PMCID: PMC9253007.

Melnick KF, Miller P, Carmichael E, McGrath K, Ghiaseddin A, Tran DD, Rahman M. The trial effect in patients with glioblastoma: effect of clinical trial enrollment on overall survival. J Neurooncol. 2022 Jul 15. doi: 10.1007/s11060-022-04083-8. [Epub ahead of print] PubMed PMID: 35840786.

Chatzkel J, Ramnaraign B, Sonpavde G. Tivozanib for the treatment of advanced renal cell carcinoma. Expert Opin Pharmacother. 2022 Jul;23(10):1135-1142. doi: 10.1080/14656566.2022.2102419. Epub 2022 Jul 25. PubMed PMID: 35848061.

Desai AV, Gilman AL, Ozkaynak MF, Naranjo A, London WB, Tenney SC, Diccianni M, Hank JA, Parisi MT, Shulkin BL, Smith M, Moscow JA, Shimada H, Matthay KK, Cohn SL, Maris JM, Bagatell R, Sondel PM, Park JR, Yu AL. Outcomes following GD2-directed postconsolidation therapy for neuroblastoma after cessation of random assignment on ANBL0032: A report from the Children’s Oncology Group. J Clin Oncol. 2022 Jul 15:JCO2102478. doi: 10.1200/JCO.21.02478. [Epub ahead of print] PubMed PMID: 35839426.

Bottomly D, Long N, Schultz AR, Kurtz SE, Tognon CE, Johnson K, Abel M, Agarwal A, Avaylon S, Benton E, Blucher A, Borate U, Braun TP, Brown J, Bryant J, Burke R, Carlos A, Chang BH, Cho HJ, Christy S, Coblentz C, Cohen AM, d’Almeida A, Cook R, Danilov A, Dao KT, Degnin M, Dibb J, Eide CA, English I, Hagler S, Harrelson H, Henson R, Ho H, Joshi SK, Junio B, Kaempf A, Kosaka Y, Laderas T, Lawhead M, Lee H, Leonard JT, Lin C, Lind EF, Liu SQ, Lo P, Loriaux MM, Luty S, Maxson JE, Macey T, Martinez J, Minnier J, Monteblanco A, Mori M, Morrow Q, Nelson D, Ramsdill J, Rofelty A, Rogers A, Romine KA, Ryabinin P, Saultz JN, Sampson DA, Savage SL, Schuff R, Searles R, Smith RL, Spurgeon SE, Sweeney T, Swords RT, Thapa A, Thiel-Klare K, Traer E, Wagner J, Wilmot B, Wolf J, Wu G, Yates A, Zhang H, Cogle CR, Collins RH, Deininger MW, Hourigan CS, Jordan CT, Lin TL, Martinez ME, Pallapati RR, Pollyea DA, Pomicter AD, Watts JM, Weir SJ, Druker BJ, McWeeney SK, Tyner JW. Integrative analysis of drug response and clinical outcome in acute myeloid leukemia. Cancer Cell. 2022 Jul 20. pii: S1535-6108(22)00312-9. doi: 10.1016/j.ccell.2022.07.002. [Epub ahead of print] PubMed PMID: 35868306.

Morgan G, Agarwal N, Choueiri TK, Dizon DS, Hamilton EP, Markham MJ, Lewis M, Prowell TM, Rugo HS, Subbiah V, West HL. The (R)evolution of social media in oncology: engage, enlighten, and encourage. Cancer Discov. 2022 Jul 6;12(7):1620-1624. doi: 10.1158/2159-8290.CD-22-0346. PubMed PMID: 35791692.

Mailhot Vega RB, Wang S, Brooks ED, Oladeru OT, Lockney NA, Spiguel LE, MacDonald SM, Mamounas EP, Mendenhall NP, Okunieff PG, Lee JH, Bradley JA. Evaluating regional nodal irradiation allocation and association with oncologic outcomes in NSABP B-18, B-27, B-40, and B-41. Int J Radiat Oncol Biol Phys. 2022 Jul 1;113(3):542-551. doi: 10.1016/j.ijrobp.2022.03.007. Epub 2022 Mar 29. PubMed PMID: 35418342; PubMed Central PMCID: PMC9250597.

Liang M, Li JW, Luo H, Lulu S, Calbay O, Shenoy A, Tan M, Law BK, Huang S, Xiao TS, Chen H, Wu L, Chang J, Lu J. Epithelial-mesenchymal transition suppresses AMPK and sensitizes cancer cells to pyroptosis under energy stress. Cells. 2022 Jul 15;11(14). pii: 2208. doi: 10.3390/cells11142208. PubMed PMID: 35883651; PubMed Central PMCID: PMC9322750.

Lü J, Jiang C, Schell TD, Joshi M, Raman JD, Xing C. Angelica gigas: Signature compounds, in vivo anticancer, analgesic, neuroprotective and other activities, and the clinical translation challenges. Am J Chin Med. 2022 Jul 23:1-53. doi: 10.1142/S0192415X2250063X. [Epub ahead of print] PubMed PMID: 35876033.

Faruqi AJ, Ligon JA, Cohen JW, Akshintala S, Widemann BC, Shah NN. Reporting of racial and ethnic minority representation in early phase pediatric oncology clinical trials. Oncologist. 2022 Jul 6. pii: oyac124. doi: 10.1093/oncolo/oyac124. [Epub ahead of print] PubMed PMID: 35791896.

Holtzman AL, Rutenberg MS, De Leo AN, Rao D, Patel J, Morris CG, Indelicato DJ, Mendenhall WM. The incidence of brainstem toxicity following high-dose conformal proton therapy for adult skull-base malignancies. Acta Oncol. 2022 Jul 27:1-6. doi: 10.1080/0284186X.2022.2101900. [Epub ahead of print] PubMed PMID: 35897132.

Ortiz-Rivera J, Albors A, Kucheryavykh Y, Harrison JK, Kucheryavykh L. The dynamics of tumor-infiltrating myeloid cell activation and the cytokine expression profile in a glioma resection site during the post-surgical period in mice. Brain Sci. 2022 Jul 7;12(7). pii: 893. doi: 10.3390/brainsci12070893. PubMed PMID: 35884700; PubMed Central PMCID: PMC9313002.

Wang CY, Park H, Heldermon CD, Vouri SM, Brown JD. Patient out-of-pocket and payer costs for pegfilgrastim originator vs biosimilars as primary prophylaxis of febrile neutropenia in the first cycle among a commercially insured population. J Manag Care Spec Pharm. 2022 Jul;28(7):795-802. doi: 10.18553/jmcp.2022.28.7.795. PubMed PMID: 35737859.

Steed T, Indelicato DJ, Souster J, van Landeghem FKH, Mehta V, Patel S. Spinal ectopic recurrence of craniopharyngioma in a pediatric patient. Childs Nerv Syst. 2022 Jul 13. doi: 10.1007/s00381-022-05604-6. [Epub ahead of print] PubMed PMID: 35831710.

Chen Z, Zhang H, George TJ, Guo Y, Prosperi M, Guo J, Braithwaite D, Wang F, Kibbe W, Wagner L, Bian J. Simulating colorectal cancer trials using real-world data. JCO Clin Cancer Inform. 2022 Jul;6:e2100195. doi: 10.1200/CCI.21.00195. PubMed PMID: 35839432.

Rotz SJ, Yi JC, Hamilton BK, Wei W, Preussler JM, Cerny J, Deol A, Jim H, Khera N, Hahn T, Hashmi SK, Holtan S, Jaglowski SM, Loren AW, McGuirk J, Reynolds J, Saber W, Savani BN, Stiff P, Uberti J, Wingard JR, Wood WA, Baker KS, Majhail NS, Syrjala KL. Health related quality of life in young adults survivors of hematopoietic cell transplantation. Transplant Cell Ther. 2022 Jul 21. pii: S2666-6367(22)01480-4. doi: 10.1016/j.jtct.2022.07.018. [Epub ahead of print] PubMed PMID: 35872304.


Mechanisms of Oncogenesis

Tang Q, Gulkis M, McKenna R, Çağlayan M. Structures of LIG1 that engage with mutagenic mismatches inserted by polβ in base excision repair. Nat Commun. 2022 Jul 5;13(1):3860. doi: 10.1038/s41467-022-31585-w. PubMed PMID: 35790757; PubMed Central PMCID: PMC9256674.

Liang M, Li JW, Luo H, Lulu S, Calbay O, Shenoy A, Tan M, Law BK, Huang S, Xiao TS, Chen H, Wu L, Chang J, Lu J. Epithelial-mesenchymal transition suppresses AMPK and sensitizes cancer cells to pyroptosis under energy stress. Cells. 2022 Jul 15;11(14). pii: 2208. doi: 10.3390/cells11142208. PubMed PMID: 35883651; PubMed Central PMCID: PMC9322750.

Wang L, Jin Z, Master RP, Maharjan CK, Carelock ME, Reccoppa TBA, Kim MC, Kolb R, Zhang W. Breast cancer stem cells: Signaling pathways, cellular interactions, and therapeutic implications. Cancers (Basel). 2022 Jul 5;14(13). pii: 3287. doi: 10.3390/cancers14133287. Review. PubMed PMID: 35805056; PubMed Central PMCID: PMC9265870.

Brakenridge SC, Chen UI, Loftus T, Ungaro R, Dirain M, Kerr A, Zhong L, Bacher R, Starostik P, Ghita G, Midic U, Darden D, Fenner B, Wacker J, Efron PA, Liesenfeld O, Sweeney TE, Moldawer LL. Evaluation of a multivalent transcriptomic metric for diagnosing surgical sepsis and estimating mortality among critically ill patients. JAMA Netw Open. 2022 Jul 1;5(7):e2221520. doi: 10.1001/jamanetworkopen.2022.21520. PubMed PMID: 35819783; PubMed Central PMCID: PMC9277492.

Mahar R, Ragavan M, Chang MC, Hardiman S, Moussatche N, Behar A, Renne R, Merritt ME. Metabolic signatures associated with oncolytic myxoma viral infections. Sci Rep. 2022 Jul 23;12(1):12599. doi: 10.1038/s41598-022-15562-3. PubMed PMID: 35871072; PubMed Central PMCID: PMC9308783.

Luo Q, Zhang J, Huang M, Lin G, Tanaka M, Lepler S, Guan J, Siemann D, Tang X. Automatic Multi-Functional Integration Program (AMFIP) towards all-optical mechano-electrophysiology interrogation. PLoS One. 2022 Jul 28;17(7):e0266098. doi: 10.1371/journal.pone.0266098. eCollection 2022. PubMed PMID: 35901062; PubMed Central PMCID: PMC9333221.

Thakur N, Wei S, Ray AP, Lamichhane R, Eddy MT. Production of human A(2A)AR in lipid nanodiscs for (19)F-NMR and single-molecule fluorescence spectroscopy. STAR Protoc. 2022 Jul 13;3(3):101535. doi: 10.1016/j.xpro.2022.101535. [Epub ahead of print] PubMed PMID: 35839771; PubMed Central PMCID: PMC9293669.