Cancer Control & Population Sciences
Cancer Therapeutics & Host Response
Cancer Control & Population Sciences
Culbert M, Oladeru OT. Clinical Trial Enrollment of Racial, Ethnic, and Underrepresented Groups-Leveraging a Digital Infrastructure. JAMA Oncol. 2021 Oct 1;7(10):1447-1448. doi: 10.1001/jamaoncol.2021.2680. PubMed PMID: 34351362.
Patra BG, Sharma MM, Vekaria V, Adekkanattu P, Patterson OV, Glicksberg B, Lepow LA, Ryu E, Biernacka JM, Furmanchuk A, George TJ, Hogan W, Wu Y, Yang X, Bian J, Weissman M, Wickramaratne P, Mann JJ, Olfson M, Campion TR, Weiner M, Pathak J. Extracting social determinants of health from electronic health records using natural language processing: a systematic review. J Am Med Inform Assoc. 2021 Oct 6. pii: ocab170. doi: 10.1093/jamia/ocab170. [Epub ahead of print] PubMed PMID: 34613399.
Thummuri D, Khan S, Underwood PW, Zheng P, Wiegand J, Zhang X, Budamagunta V, Sobh A, Tagmount A, Loguinov A, Riner AN, Akki AS, Williamson E, Hromas R, Vulpe CD, Zheng G, Trevino JG, Zhou D. Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL Specific Degrader DT2216. Mol Cancer Ther. 2021 Oct 19. pii: molcanther.MCT-21-0474-A.2021. doi: 10.1158/1535-7163.MCT-21-0474. [Epub ahead of print] PubMed PMID: 34667112
Hogan WR, Shenkman EA, Robinson T, Carasquillo O, Robinson PS, Essner RZ, Bian J, Lipori G, Harle C, Magoc T, Manini L, Mendoza T, White S, Loiacono A, Hall J, Nelson D. The OneFlorida Data Trust: a centralized, translational research data infrastructure of statewide scope. J Am Med Inform Assoc. 2021 Oct 19. pii: ocab221. doi: 10.1093/jamia/ocab221. [Epub ahead of print] PubMed PMID: 34664656.
Richesson RL, Marsolo KS, Douthit BJ, Staman K, Ho PM, Dailey D, Boyd AD, McTigue KM, Ezenwa MO, Schlaeger JM, Patil CL, Faurot KR, Tuzzio L, Larson EB, O’Brien EC, Zigler CK, Lakin JR, Pressman AR, Braciszewski JM, Grudzen C, Fiol GD. Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory. J Am Med Inform Assoc. 2021 Oct 1. pii: ocab202. doi: 10.1093/jamia/ocab202. [Epub ahead of print] PubMed PMID: 34597383.
Edmondson MJ, Luo C, Duan R, Maltenfort M, Chen Z, Locke K Jr, Shults J, Bian J, Ryan PB, Forrest CB, Chen Y. An efficient and accurate distributed learning algorithm for modeling multi-site zero-inflated count outcomes. Sci Rep. 2021 Oct 4;11(1):19647. doi: 10.1038/s41598-021-99078-2. PubMed PMID: 34608222; PubMed Central PMCID: PMC8490431
Herremans KM, Cribbin MP, Riner AN, Neal DW, Hollen TL, Clevenger P, Munoz D, Blewett S, Giap F, Okunieff PG, Mendenhall NP, Bradley JA, Mendenhall WM, Vega RBM, Brooks E, Daily KC, Heldermon CD, Marshall JK, Hanna MW, Leyngold MM, Virk SS, Shaw CM, Spiguel LR. ASO Visual Abstract: A 5-Year Breast Surgeon Experience in LYMPHA at Time of ALND for Treatment of Clinical T1-4N1-3M0Â Breast Cancer. Ann Surg Oncol. 2021 Oct 16. doi: 10.1245/s10434-021-10648-0. [Epub ahead of print] PubMed PMID: 34655351.
Ma SJ, Serra LM, Yu B, Bartl AJ, Farrugia MK, Oladeru OT, Singh AK. Evaluation of risk stratification using gene expression assays in patients with breast cancer receiving neoadjuvant chemotherapy. Breast Cancer Res Treat. 2021 Oct;189(3):737-745. doi: 10.1007/s10549-021-06269-6. Epub 2021 Sep 14. PubMed PMID: 34519904.
Kauark-Fontes E, Migliorati CA, Epstein JB, Treister NS, Alves CGB, Faria KM, Palmier NR, Rodrigues-Oliveira L, de Pauli Paglioni M, Gueiros LAM, da Conceição Vasconcelos KGM, de Castro G Jr, Leme AFP, Lopes MA, Prado-Ribeiro AC, Brandão TB, Santos-Silva AR. Extraoral photobiomodulation for prevention of oral and oropharyngeal mucositis in head and neck cancer patients: interim analysis of a randomized, double-blind, clinical trial. Support Care Cancer. 2021 Oct 28. doi: 10.1007/s00520-021-06625-8. [Epub ahead of print] PubMed PMID: 34708311; PubMed Central PMCID: PMC8550910.
Kastrinos AL, Bylund CL, Mullis MD, Wollney E, Sae-Hau M, Weiss E, Fisher CL. Parents Caring for Children Diagnosed with a Blood Cancer from Infancy to Emerging Adulthood: A Life span Perspective. J Adolesc Young Adult Oncol. 2021 Oct 12. doi: 10.1089/jayao.2021.0070. [Epub ahead of print] PubMed PMID: 34647791.
Fabregas JC, Carter BT, Lutzky J, Robinson WR 3rd, Brant JM. Impact of Medicaid Expansion Status and Race on Metastatic Disease at Diagnosis in Patients with Melanoma. J Racial Ethn Health Disparities. 2021 Oct 14. doi: 10.1007/s40615-021-01166-6. [Epub ahead of print] PubMed PMID: 34648145.
Martins BNFL, Palmier NR, Prado-Ribeiro AC, de Goes MF, Lopes MA, Brandão TB, Rivera C, Migliorati CA, Epstein JB, Santos-Silva AR. Awareness of the risk of radiation-related caries in patients with head and neck cancer: A survey of physicians, dentists, and patients. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Oct;132(4):398-408. doi: 10.1016/j.oooo.2021.06.011. Epub 2021 Jun 21. PubMed PMID: 34353769.
Hochhegger B, Marchiori E, Rodrigues R, Mançano A, Jasinowodolinski D, Chate RC, Souza AS Jr, Silva AM, Sawamura M, Furnari M, Araujo-Neto C, Escuissato D, Pinetti R, Nobre LF, Warszawiak D, Szarf G, Telles GBDS, Meirelles G, Santana PR, Antunes V, Capobianco J, Missrie I, Souza LVS, Santos MK, Irion K, Duarte I, Santos R, Pinto E, Penha D. Consensus statement on thoracic radiology terminology in Portuguese used in Brazil and in Portugal. J Bras Pneumol. 2021 Oct 15;47(5):e20200595. doi: 10.36416/1806-3756/e20200595. eCollection 2021. Review. English, Portuguese. PubMed PMID: 34669832.
Griffin KT, Sato T, Funamoto S, Chizhov K, Domal S, Paulbeck C, Bolch W, Cullings HM, Egbert S, Endo A, Hertel N, Lee C. Japanese pediatric and adult atomic bomb survivor dosimetry: potential improvements using the J45 phantom series and modern Monte Carlo transport. Radiat Environ Biophys. 2021 Oct 30. doi: 10.1007/s00411-021-00946-2. [Epub ahead of print] PubMed PMID: 34718851.
Cousin L, Roper N, Nolan TS. Cardio-Oncology Health Disparities: Social Determinants of Health and Care for Black Breast Cancer Survivors. Clin J Oncol Nurs. 2021 Oct 1;25(5):36-41. doi: 10.1188/21.CJON.S1.36-41. PubMed PMID: 34533529; PubMed Central PMCID: PMC8560214.
Suk R, Hong YR, Wasserman RM, Swint JM, Azenui NB, Sonawane KB, Tsai AC, Deshmukh AA. Analysis of Suicide After Cancer Diagnosis by US County-Level Income and Rural vs Urban Designation, 2000-2016. JAMA Netw Open. 2021 Oct 1;4(10):e2129913. doi: 10.1001/jamanetworkopen.2021.29913. PubMed PMID: 34665238.
Wang Y, Zhao Y, Schutte D, Bian J, Zhang R. Deep learning models in detection of dietary supplement adverse event signals from Twitter. JAMIA Open. 2021 Oct 8;4(4):ooab081. doi: 10.1093/jamiaopen/ooab081. eCollection 2021 Oct. PubMed PMID: 34632323; PubMed Central PMCID: PMC8497875.
Cancer Therapeutics & Host Response
Pernigoni N, Zagato E, Calcinotto A, Troiani M, Mestre RP, Calì B, Attanasio G, Troisi J, Minini M, Mosole S, Revandkar A, Pasquini E, Elia AR, Bossi D, Rinaldi A, Rescigno P, Flohr P, Hunt J, Neeb A, Buroni L, Guo C, Welti J, Ferrari M, Grioni M, Gauthier J, Gharaibeh RZ, Palmisano A, Lucchini GM, D’Antonio E, Merler S, Bolis M, Grassi F, Esposito A, Bellone M, Briganti A, Rescigno M, Theurillat JP, Jobin C, Gillessen S, de Bono J, Alimonti A. Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis. Science. 2021 Oct 8;374(6564):216-224. doi: 10.1126/science.abf8403. Epub 2021 Oct 7. PubMed PMID: 34618582.
Thummuri D, Khan S, Underwood PW, Zheng P, Wiegand J, Zhang X, Budamagunta V, Sobh A, Tagmount A, Loguinov A, Riner AN, Akki AS, Williamson E, Hromas R, Vulpe CD, Zheng G, Trevino JG, Zhou D. Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL Specific Degrader DT2216. Mol Cancer Ther. 2021 Oct 19. pii: molcanther.MCT-21-0474-A.2021. doi: 10.1158/1535-7163.MCT-21-0474. [Epub ahead of print] PubMed PMID: 34667112.
Leavey PJ, Laack NN, Krailo MD, Buxton A, Randall RL, DuBois SG, Reed DR, Grier HE, Hawkins DS, Pawel B, Nadel H, Womer RB, Letson GD, Bernstein M, Brown K, Maciej A, Chuba P, Ahmed AA, Indelicato DJ, Wang D, Marina N, Gorlick R, Janeway KA, Mascarenhas L. Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children’s Oncology Group Report. J Clin Oncol. 2021 Oct 15:JCO2100358. doi: 10.1200/JCO.21.00358. [Epub ahead of print] PubMed PMID: 34652968.
Liu APY, Smith KS, Kumar R, Paul L, Bihannic L, Lin T, Maass KK, Pajtler KW, Chintagumpala M, Su JM, Bouffet E, Fisher MJ, Gururangan S, Cohn R, Hassall T, Hansford JR, Klimo P Jr, Boop FA, Stewart CF, Harreld JH, Merchant TE, Tatevossian RG, Neale G, Lear M, Klco JM, Orr BA, Ellison DW, Gilbertson RJ, Onar-Thomas A, Gajjar A, Robinson GW, Northcott PA. Serial assessment of measurable residual disease in medulloblastoma liquid biopsies. Cancer Cell. 2021 Oct 19. pii: S1535-6108(21)00501-8. doi: 10.1016/j.ccell.2021.09.012. [Epub ahead of print] PubMed PMID: 34678152.
Kim MC, Borcherding N, Ahmed KK, Voigt AP, Vishwakarma A, Kolb R, Kluz PN, Pandey G, De U, Drashansky T, Helm EY, Zhang X, Gibson-Corley KN, Klesney-Tait J, Zhu Y, Lu J, Lu J, Huang X, Xiang H, Cheng J, Wang D, Wang Z, Tang J, Hu J, Wang Z, Liu H, Li M, Zhuang H, Avram D, Zhou D, Bacher R, Zheng SG, Wu X, Zakharia Y, Zhang W. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nat Commun. 2021 Oct 1;12(1):5764. doi: 10.1038/s41467-021-26091-4. PubMed PMID: 34599187; PubMed Central PMCID: PMC8486774.
Lazow MA, Fuller C, DeWire M, Lane A, Bandopadhayay P, Bartels U, Bouffet E, Cheng S, Cohen KJ, Cooney TM, Coven SL, Dholaria H, Diez B, Dorris K, El-Ayadi M, El-Sheikh A, Fisher PG, Fonseca A, Lombardi MG, Greiner RJ, Goldman S, Gottardo N, Gururangan S, Hansford JR, Hassall T, Hawkins C, Kilburn L, Koschmann C, Leary SE, Ma J, Minturn JE, Monje-Deisseroth M, Packer R, Samson Y, Sandler ES, Sevlever G, Tinkle CL, Tsui K, Wagner LM, Zaghloul M, Ziegler DS, Chaney B, Black K, Asher A, Drissi R, Fouladi M, Jones BV, Leach JL. Accuracy of Central Neuro-Imaging Review of DIPG Compared with Histopathology in the International DIPG Registry. Neuro Oncol. 2021 Oct 20. pii: noab245. doi: 10.1093/neuonc/noab245. [Epub ahead of print] PubMed PMID: 34668975.
Venugopal K, Feng Y, Nowialis P, Xu H, Shabashvili DE, Berntsen CM, Kaur P, Krajcik KI, Taragjini C, Zaroogian Z, Casellas Roman HL, Posada LM, Gunaratne C, Li J, Dupere-Richer D, Bennett RL, Pondugula S, Riva A, Cogle CR, Opavsky R, Law BK, Bhaduri-McIntosh S, Kubicek S, Staber PB, Licht JD, Bird JE, Guryanova OA. DNMT3A harboring leukemia-associated mutations directs sensitivity to DNA damage at replication forks. Clin Cancer Res. 2021 Oct 29. pii: clincanres.2863.2021. doi: 10.1158/1078-0432.CCR-21-2863. [Epub ahead of print] PubMed PMID: 34716195.
Patra BG, Sharma MM, Vekaria V, Adekkanattu P, Patterson OV, Glicksberg B, Lepow LA, Ryu E, Biernacka JM, Furmanchuk A, George TJ, Hogan W, Wu Y, Yang X, Bian J, Weissman M, Wickramaratne P, Mann JJ, Olfson M, Campion TR, Weiner M, Pathak J. Extracting social determinants of health from electronic health records using natural language processing: a systematic review. J Am Med Inform Assoc. 2021 Oct 6. pii: ocab170. doi: 10.1093/jamia/ocab170. [Epub ahead of print] PubMed PMID: 34613399.
Melnick K, Shin D, Dastmalchi F, Kabeer Z, Rahman M, Tran D, Ghiaseddin A. Role of Laser Interstitial Thermal Therapy in the Management of Primary and Metastatic Brain Tumors. Curr Treat Options Oncol. 2021 Oct 23;22(12):108. doi: 10.1007/s11864-021-00912-6. Review. PubMed PMID: 34687357.
Cao Y, Chen H, Sahgal A, Erler D, Badellino S, Biswas T, Dagan R, Foote MC, Louie AV, Poon I, Ricardi U, Redmond KJ. Volumetric burden of metastatic lesions drives outcomes in patients with extracranial oligometastatic disease. Cancer Med. 2021 Oct 20. doi: 10.1002/cam4.4332. [Epub ahead of print] PubMed PMID: 34668651.
Hrebinko KA, Reitz KM, Mohammed MK, Nassour I, Watson AR, Cunningham KE, Medich DS, Celebrezze JP, Holder-Murray JM. Transanal excision with adjuvant therapy for pT1N0 rectal tumors with high-risk features offers equivalent survival to radical resection: A National Cancer Database analysis. J Surg Oncol. 2021 Oct 27. doi: 10.1002/jso.26734. [Epub ahead of print] PubMed PMID: 34705273.
Dagan R, Galloway TJ. Radiation Treatment Deintensification for HPV-Associated Oropharyngeal Cancer. Semin Radiat Oncol. 2021 Oct;31(4):324-331. doi: 10.1016/j.semradonc.2021.02.010. Review. PubMed PMID: 34455987.
Guha A, Gong Y, DeRemer D, Owusu-Guha J, Dent SF, Cheng RK, Weintraub NL, Agarwal N, Fradley MG. Cardiometabolic consequences of targeted anticancer therapies. J Cardiovasc Pharmacol. 2021 Oct 4. doi: 10.1097/FJC.0000000000001149. [Epub ahead of print] PubMed PMID: 34654781.
Chazan G, Jupp J, Bauters T, Duncan N, Weddle KJ, Nomura H, O’Connor S, Chan A, Alkhudair N, Alshamrani M, Buie LW, Chambers P, Chieh TW, DeRemer DL, Duvivier F, Katabalo D, McFarlane T, Mckavanagh D, Mensah K, Martinez EM, Rowan G, Sae-Teaw M, Tadesse TA, Weru I, Alexander M. Impact of coronavirus of 2019 on the delivery of pharmacy services to patients with cancer: An international survey of oncology pharmacy practitioners. J Oncol Pharm Pract. 2021 Oct 23:10781552211048892. doi: 10.1177/10781552211048892. [Epub ahead of print] PubMed PMID: 34693814.
Harding K, De Mello Souza CH, Shiomitsu K, Maxwell E, Bertran J. C-kit, flt-3, PDGFR-β, and VEGFR2 expression in canine adrenal tumors and correlation with outcome following adrenalectomy. Can J Vet Res. 2021 Oct;85(4):279-284. PubMed PMID: 34602732; PubMed Central PMCID: PMC8451711.
Cancio M, Hebert K, Kim S, Aljurf M, Olson T, Anderson E, Burroughs L, Vatsayan A, Myers K, Hashem H, Hanna R, Horn B, Prestidge T, Boelens JJ, Boulad F, Eapen M. Outcomes in Hematopoietic Stem Cell Transplantation for Congenital Amegakaryocytic Thrombocytopenia. Transplant Cell Ther. 2021 Oct 17. pii: S2666-6367(21)01299-9. doi: 10.1016/j.jtct.2021.10.009. [Epub ahead of print] PubMed PMID: 34670170.
Knewitz DK, Anderson CJ, Presley WT, Horodyski M, Scarborough MT, Wallace MR. Survival and NF1 Analysis in a Cohort of Orthopedics Patients with Malignant Peripheral Nerve Sheath Tumors. Sarcoma. 2021 Oct 4;2021:9386823. doi: 10.1155/2021/9386823. eCollection 2021. PubMed PMID: 34646065; PubMed Central PMCID: PMC8505086.
Mechanisms of Oncogenesis
Kim MC, Borcherding N, Ahmed KK, Voigt AP, Vishwakarma A, Kolb R, Kluz PN, Pandey G, De U, Drashansky T, Helm EY, Zhang X, Gibson-Corley KN, Klesney-Tait J, Zhu Y, Lu J, Lu J, Huang X, Xiang H, Cheng J, Wang D, Wang Z, Tang J, Hu J, Wang Z, Liu H, Li M, Zhuang H, Avram D, Zhou D, Bacher R, Zheng SG, Wu X, Zakharia Y, Zhang W. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nat Commun. 2021 Oct 1;12(1):5764. doi: 10.1038/s41467-021-26091-4. PubMed PMID: 34599187; PubMed Central PMCID: PMC8486774.
Fujiwara Y, Torphy RJ, Sun Y, Miller EN, Ho F, Borcherding N, Wu T, Torres RM, Zhang W, Schulick RD, Zhu Y. The GPR171 pathway suppresses T cell activation and limits antitumor immunity. Nat Commun. 2021 Oct 6;12(1):5857. doi: 10.1038/s41467-021-26135-9. PubMed PMID: 34615877; PubMed Central PMCID: PMC8494883.
Zolotukhin S, Trivedi PD, Corti M, Byrne BJ. Scratching the surface of RGD-directed AAV capsid engineering. Mol Ther. 2021 Oct 25. pii: S1525-0016(21)00527-X. doi: 10.1016/j.ymthe.2021.10.020. [Epub ahead of print] PubMed PMID: 34699781.
Thummuri D, Khan S, Underwood PW, Zheng P, Wiegand J, Zhang X, Budamagunta V, Sobh A, Tagmount A, Loguinov A, Riner AN, Akki AS, Williamson E, Hromas R, Vulpe CD, Zheng G, Trevino JG (CCPS*), Zhou D. Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL Specific Degrader DT2216. Mol Cancer Ther. 2021 Oct 19. pii: molcanther.MCT-21-0474-A.2021. doi: 10.1158/1535-7163.MCT-21-0474. [Epub ahead of print] PubMed PMID: 34667112.
Knewitz DK, Anderson CJ, Presley WT, Horodyski M, Scarborough MT, Wallace MR. Survival and NF1 Analysis in a Cohort of Orthopedics Patients with Malignant Peripheral Nerve Sheath Tumors. Sarcoma. 2021 Oct 4;2021:9386823. doi: 10.1155/2021/9386823. eCollection 2021. PubMed PMID: 34646065; PubMed Central PMCID: PMC8505086.
Gay LA, Turner PC, Renne R. Modified Cross-Linking, Ligation, and Sequencing of Hybrids (qCLASH) to Identify MicroRNA Targets. Curr Protoc. 2021 Oct;1(10):e257. doi: 10.1002/cpz1.257. PubMed PMID: 34610213; PubMed Central PMCID: PMC8500481.