Fighting pediatric cancer focus of V Foundation-UF Health collaboration

In pursuit of its ongoing mission to achieve Victory Over Cancer®, the V Foundation for Cancer Research announced its renewed support and a new $250,000 grant for the University of Florida’s efforts to combat brain cancer in children. Combined with private support, a total of $600,000 in new funding will bolster critical research programs.

Florida cancer hospitals get $100 million for research

Gov. Ron DeSantis announced that he will approve $100 million for cancer research and treatment in the state’s 2022-2023 spending plan — an increase of about $37 million over the current budget. Three Florida cancer centers — the UF Health Cancer Center, Sylvester Comprehensive Cancer Center and H. Lee Moffitt Cancer Center and Research Institute — will receive the funding for research and medical care.

UF to test novel CAR-modified T-cell technique in clinical trial for glioblastoma

University of Florida researchers have received approval from the Food and Drug Administration to test an investigational new therapy in a first-in-human clinical trial for participants with primary glioblastoma, the most aggressive malignant brain tumor.

The Phase I trial, expected to begin this fall and enroll 24 patients over age 18, will be led by Jianping Huang, M.D., Ph.D., and Ashley Ghiaseddin, M.D.

Researchers’ discovery advances knowledge of key cellular function

The role of ribosomes in converting genetic code into protein molecules is well known. Despite that, much less is known about how ribosomes arise. More surprisingly, recent discoveries have indicated different “flavors” of ribosomes produce different proteins.
Now, researchers at Scripps Research’s Florida campus have discovered how normal ribosomes are “remodeled” into different subtypes as a response to cellular stress.

Janice Krieger, CJC doctoral student and colleagues co-author article on colorectal cancer screening message strategies

According to the authors: “The current study demonstrated that a tailored risk message increased perceptions of message relevance and susceptibility to colorectal cancer, which increased patient intentions to screen for colorectal cancer. Findings offer a low-burden, practical approach to evaluate and improve health education materials that promote screening.”