Cancer Control and Population Sciences
Braithwaite D, Karanth SD, Divaker J, Shoenborn N, Lin K, Richman I, Hochhegger B, O’Neill S, Schonberg M. Evaluating ChatGPT’s accuracy in providing screening mammography recommendations among older women: Artificial Intelligence and cancer communication. J Am Geriatr Soc. 2024 Jul;72(7):2237-2240. doi: 10.1111/jgs.18854. Epub 2024 Mar 14. No abstract available. PubMed PMID: 38485652.
Tantawy M, Langaee T, Wang D, Rubinstein SM, Cornell RF, Lenihan D, Fradley MG, Gong Y. Differential Expression of Circulating miRNAs and Carfilzomib-Related Cardiovascular Adverse Events in Patients with Multiple Myeloma. Int J Mol Sci. 2024 Jul 16;25(14):7795. doi: 10.3390/ijms25147795. PubMed PMID: 39063038; PubMed Central PMCID: PMC11276722.
Hu Q, Tang Z, Lynch A, Freeman B, Fujioka N, Salloum RG, Malaty J, Orlando FA, Langaee T, Huo Z, Xing C. One-Week Kava Dietary Supplementation Increases Both Urinary N- and O-Glucuronides of NNAL, a Lung Carcinogen Major Metabolite, among Smokers. Chem Res Toxicol. 2024 Jul 13. doi: 10.1021/acs.chemrestox.4c00109. Online ahead of print. PubMed PMID: 39001862.
Bagautdinova D, Bylund CL, Forthun LF, Miller CA, Hamel LM, Fisher CL. Helping adolescents and young adults (AYA) with cancer manage identity distress: Enhancing clinician-AYA patient communication to promote identity development. Patient Educ Couns. 2024 Jul 7;128:108372. doi: 10.1016/j.pec.2024.108372. Online ahead of print. PubMed PMID: 39029282.
Oladeru O, Rajack F, Esnakula A, Naab TJ, Kanaan Y, Ricks-Santi L. Beyond Triple-Negative: High Prevalence of Quadruple-Negative Breast Cancer in African Americans. Biomedicines. 2024 Jul 9;12(7):1522. doi: 10.3390/biomedicines12071522. PubMed PMID: 39062096; PubMed Central PMCID: PMC11275194.
Dong Y, Gong K. Head and neck tumor segmentation from [18F]F-FDG PET/CT images based on 3D diffusion model. Phys Med Biol. 2024 Jul 16;69(15). doi: 10.1088/1361-6560/ad5ef2. PubMed PMID: 38959909.
Allard-Phillips E, Christman GM, Williams RS, Filipp SL, Snyder D, Chang P, Rhoton-Vlasak A. Fertility in the Digital Age: A Survey-Based Evaluation of Fertility App Users’ Quality of Life. Reprod Sci. 2024 Jul 15. doi: 10.1007/s43032-024-01650-4. Online ahead of print. PubMed PMID: 39009913.
Sajdeya R, Rouhizadeh M, Cook RL, Ison RL, Bai C, Jugl S, Gao H, Mardini MT, Zandbiglari K, Adiba FI, Dasa O, Winterstein AG, Price CC, Pearson TA, Seubert CN, Tighe PJ. Cannabis Use and Inhalational Anesthesia Administration in Older Adults: A Propensity Matched Retrospective Cohort Study. Anesthesiology. 2024 Jul 9. doi: 10.1097/ALN.0000000000005146. Online ahead of print. PubMed PMID: 38980341.
Tang H, Lu Y, Donahoo WT, Shao H, Shi L, Fonseca VA, Guo Y, Bian J, Guo J. Glucagon-Like Peptide-1 Receptor Agonists and Risk for Suicidal Ideation and Behaviors in U.S. Older Adults With Type 2 Diabetes : A Target Trial Emulation Study. Ann Intern Med. 2024 Jul 16. doi: 10.7326/M24-0329. Online ahead of print. PubMed PMID: 39008852.
Heng YJ, Baker GM, Fein-Zachary VJ, Guzman-Arocho YD, Bret-Mounet VC, Massicott ES, Torous VF, Schnitt SJ, Gitin S, Russo P, Tobias AM, Bartlett RA, Varma G, Kontos D, Yaghjyan L, Irwig MS, Potter JE, Wulf GM. Effect of testosterone therapy on breast tissue composition and mammographic breast density in trans masculine individuals. Breast Cancer Res. 2024 Jul 2;26(1):109. doi: 10.1186/s13058-024-01867-w. PubMed PMID: 38956693; PubMed Central PMCID: PMC11221014.
Mendenhall NP. Bringing proton therapy to India: The recent article from Gupta et al. on revolutionizing cancer treatment in India. Cancer. 2024 Jul 15;130(14):2413-2415. doi: 10.1002/cncr.35320. Epub 2024 Apr 27. No abstract available. PubMed PMID: 38676930.
Howell K, Garvan C, Amini S, Kamyszek RW, Tighe P, Price CC, Spiess BD; PeCAN Program Study Group. Association Between Preoperative Anemia and Cognitive Function in a Large Cohort Study of Older Patients Undergoing Elective Surgery. Anesth Analg. 2024 Jul 5. doi: 10.1213/ANE.0000000000006998. Online ahead of print. PubMed PMID: 38985884.
Kaufmann CN, Bai C, Borgia B, Leeuwenburgh C, Lin Y, Mardini MT, McElroy T, Swanson CW, Wimberly KD, Zapata R, Zeidan RS, Manini TM. ChatGPT’s Role in Gerontology Research. J Gerontol A Biol Sci Med Sci. 2024 Jul 24:glae184. doi: 10.1093/gerona/glae184. Online ahead of print. PubMed PMID: 39046716.
Bae J, Tantawy M, Gong Y, Langaee T, Lartey M, Ganu V, Tachi K, Ojewale O, Obo-Akwa A, Boamah I, Bushman LR, Ellison L, Yang H, Anderson PL, Kwara A. Pharmacogenetic determinants of tenofovir diphosphate and lamivudine triphosphate concentrations in people with HIV/HBV coinfection. Antimicrob Agents Chemother. 2024 Jul 30:e0054924. doi: 10.1128/aac.00549-24. Online ahead of print. PubMed PMID: 39078131.
Cicali EJ, Eddy E, Gong Y, Elchynski AL, Pena Del Aguila K, Basha T, Daily KC, Dickson L, Fischer S, Hastings-Monari E, Jones D Jr, Ramnaraign BH, DeRemer DL, George TJ, Cooper-DeHoff RM. Implementation of a pharmacogenetic panel-based test for pharmacotherapy-based supportive care in an adult oncology clinic. Clin Transl Sci. 2024 Jul;17(7):e13890. doi: 10.1111/cts.13890. PubMed PMID: 39046302; PubMed Central PMCID: PMC11267631.
Kasner M, Fritsche AH, Leong MC, Cameron K, Lee CB, Lin TL, Lee JH, Brogan F, Kovak MR, Honeycutt H, Shaw K, George TJ. North American Cancer Center Clinical Research Capacity and Benchmarking in the Postpandemic Era. JCO Oncol Pract. 2024 Jul 1:OP2400164. doi: 10.1200/OP.24.00164. Online ahead of print. PubMed PMID: 38950320.
Yarom N, Van Poznak CH, Epstein JB, Ottaviani G, Matsuda Y, Migliorati C, Elad S. MASCC/ISOO Clinical Practice Statement: Adjuvant bone-modifying agents in primary breast cancer patients – prevention of medication-related osteonecrosis of the jaw. Support Care Cancer. 2024 Jul 25;32(8):547. doi: 10.1007/s00520-024-08687-w. PubMed PMID: 39048887; PubMed Central PMCID: PMC11269502.
Zhou SR, Choi MH, Vesal S, Kinnaird A, Brisbane WG, Lughezzani G, Maffei D, Fasulo V, Albers P, Zhang L, Kornberg Z, Fan RE, Shao W, Rusu M, Sonn GA. Inter-reader Agreement for Prostate Cancer Detection Using Micro-ultrasound: A Multi-institutional Study. Eur Urol Open Sci. 2024 Jul 13;66:93-100. doi: 10.1016/j.euros.2024.06.017. eCollection 2024 Aug. PubMed PMID: 39076245; PubMed Central PMCID: PMC11284543.
Guha S, Li Y. Causal meta-analysis by integrating multiple observational studies with multivariate outcomes. Biometrics. 2024 Jul 1;80(3):ujae070. doi: 10.1093/biomtc/ujae070. PubMed PMID: 39073772; PubMed Central PMCID: PMC11285113.
Zang C, Hou Y, Schenck EJ, Xu Z, Zhang Y, Xu J, Bian J, Morozyuk D, Khullar D, Nordvig AS, Shenkman EA, Rothman RL, Block JP, Lyman K, Zhang Y, Varma J, Weiner MG, Carton TW, Wang F, Kaushal R. Identification of risk factors of Long COVID and predictive modeling in the RECOVER EHR cohorts. Commun Med (Lond). 2024 Jul 11;4(1):130. doi: 10.1038/s43856-024-00549-0. PubMed PMID: 38992068; PubMed Central PMCID: PMC11239808.
He X, Wei R, Huang Y, Chen Z, Lyu T, Bost S, Tong J, Li L, Zhou Y, Li Z, Guo J, Tang H, Wang F, DeKosky S, Xu H, Chen Y, Zhang R, Xu J, Guo Y, Wu Y, Bian J. Develop and validate a computable phenotype for the identification of Alzheimer’s disease patients using electronic health record data. Alzheimers Dement (Amst). 2024 Jul 3;16(3):e12613. doi: 10.1002/dad2.12613. eCollection 2024 Jul-Sep. PubMed PMID: 38966622; PubMed Central PMCID: PMC11220631.
Cancer Targeting and Therapeutics
Tong Y, Su X, Rouse W, Childs-Disney JL, Taghavi A, Zanon PRA, Kovachka S, Wang T, Moss WN, Disney MD. Transcriptome-Wide, Unbiased Profiling of Ribonuclease Targeting Chimeras. J Am Chem Soc. 2024 Jul 24. doi: 10.1021/jacs.4c04717. Online ahead of print. PubMed PMID: 39047145.
Marrero RJ, Wu H, Cao X, Parcha PK, Elsayed AH, Inaba H, Kuo DJ, Degar BA, Heym K, Taub JW, Lacayo N, Pui CH, Ribeiro RC, Rubnitz JE, Pounds SB, Lamba JK. Pharmacogenomic Score Effectively Personalizes Treatment of Acute Myeloid Leukemia. Clin Cancer Res. 2024 Jul 30. doi: 10.1158/1078-0432.CCR-24-0863. Online ahead of print. PubMed PMID: 39078289.
Xiao Y, Awasthee N, Liu Y, Meng C, He MY, Hale S, Karki R, Lin Z, Mosterio M, Garcia BA, Kridel R, Liao D, Zheng G. Discovery of a Highly Potent and Selective HDAC8 Degrader: Advancing the Functional Understanding and Therapeutic Potential of HDAC8. J Med Chem. 2024 Jul 1. doi: 10.1021/acs.jmedchem.4c00761. Online ahead of print. PubMed PMID: 38949959.
Kasner M, Fritsche AH, Leong MC, Cameron K, Lee CB, Lin TL, Lee JH, Brogan F, Kovak MR, Honeycutt H, Shaw K, George TJ. North American Cancer Center Clinical Research Capacity and Benchmarking in the Postpandemic Era. JCO Oncol Pract. 2024 Jul 1:OP2400164. doi: 10.1200/OP.24.00164. Online ahead of print. PubMed PMID: 38950320.
Adedokun G, Alipanah M, Fan ZH. Sample preparation and detection methods in point-of-care devices towards future at-home testing. Lab Chip. 2024 Jul 23;24(15):3626-3650. doi: 10.1039/d3lc00943b. PubMed PMID: 38952234; PubMed Central PMCID: PMC11270053.
Chen JL, Taghavi A, Frank AJ, Fountain MA, Choudhary S, Roy S, Childs-Disney JL, Disney MD. NMR structures of small molecules bound to a model of a CUG RNA repeat expansion. Bioorg Med Chem Lett. 2024 Jul 14;111:129888. doi: 10.1016/j.bmcl.2024.129888. Online ahead of print. PubMed PMID: 39002937.
von Roemeling CA, Patel JA, Carpenter SL, Yegorov O, Yang C, Bhatia A, Doonan BP, Russell R, Trivedi VS, Klippel K, Ryu DH, Grippin A, Futch HS, Ran Y, Hoang-Minh LB, Weidert FL, Golde TE, Mitchell DA. Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade. Nat Commun. 2024 Jul 12;15(1):5871. doi: 10.1038/s41467-024-49989-1. PubMed PMID: 38997283; PubMed Central PMCID: PMC11245621.
Alexander S, Kairalla JA, Gupta S, Hibbitts E, Weisman H, Anghelescu D, Winick NJ, Krull KR, Salzer WL, Burke MJ, Gore L, Devidas M, Embry L, Raetz EA, Hunger SP, Loh ML, Hardy KK. Reply to C.T. Matava et al. J Clin Oncol. 2024 Jul 24:JCO2401244. doi: 10.1200/JCO-24-01244. Online ahead of print. No abstract available. PubMed PMID: 39047217.
Xiao Y, Yuan Y, Liu Y, Lin Z, Zheng G, Zhou D, Lv D. Targeted Protein Degradation: Current and Emerging Approaches for E3 Ligase Deconvolution. J Med Chem. 2024 Jul 25;67(14):11580-11596. doi: 10.1021/acs.jmedchem.4c00723. Epub 2024 Jul 9. PubMed PMID: 38981094.
Li JS, Blanchard P, Wong CHL, Ahn YC, Bonomo P, Bresson D, Caudell J, Chen MY, Chow VLY, Chua MLK, Corry J, Dupin C, Giralt J, Hu C, Kwong DLW, Le QT, Lee AWM, Lee NY, Li Y, Lim CM, Lin JC, Mendenhall WM, Moya-Plana A, O’Sullivan B, Ozyar E, Pan J, Qiu Q, Sher DJ, Snyderman CH, Tao Y, Tsang RK, Wang X, Wu P, Yom SS, Ng WT. International Recommendations on Postoperative Management for Potentially Resectable Locally Recurrent Nasopharyngeal Carcinoma. Int J Radiat Oncol Biol Phys. 2024 Jul 13:S0360-3016(24)02954-7. doi: 10.1016/j.ijrobp.2024.07.2143. Online ahead of print. PubMed PMID: 39009321.
Johnson PB, Mamalui M, Brodin P, Janssens G. Secondary cancer risk in six anatomical sites when using PAT, IMPT, and VMAT/IMRT radiotherapy. Radiother Oncol. 2024 Jul 10;199:110421. doi: 10.1016/j.radonc.2024.110421. Online ahead of print. PubMed PMID: 38997093.
Pratt VM, Cavallari LH, Fulmer ML, Gaedigk A, Hachad H, Ji Y, Kalman LV, Ly RC, Moyer AM, Scott SA, Turner AJ, van Schaik RHN, Whirl-Carrillo M, Weck KE. DPYD Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, American College of Medical Genetics and Genomics, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, Pharmacogenomics Knowledgebase, and Pharmacogene Variation Consortium. J Mol Diagn. 2024 Jul 18:S1525-1578(24)00154-5. doi: 10.1016/j.jmoldx.2024.05.015. Online ahead of print. PubMed PMID: 39032821.
Kokkaliari S, Grauso L, Mangoni A, Seabra G, Paul VJ, Luesch H. Isolation, Structure Elucidation, and Biological Activity of the Selective TACR2 Antagonist Tumonolide and its Aldehyde from a Marine Cyanobacterium. Chemistry. 2024 Jul 18:e202401393. doi: 10.1002/chem.202401393. Online ahead of print. PubMed PMID: 39023398.
Alvarez JA, Shi Q, Dasari A, Garcia-Aguilar J, Sanoff H, George TJ, Hong T, Yothers G, Philip P, Nelson G, Al Baghdadi T, Alese OB, Zambare W, Omer D, Verheij FS, Bercz A, Kim MJ, Buckley J, Williams H, George M, Garcia R, Gallagher P, O’Reilly EM, Meyerhardt JA, Crawley J, Shergill A, Horvat N, Romesser PB, Hall W, Smith JJ. Alliance A022104/NRG-GI010: The Janus Rectal Cancer Trial: a randomized phase II/III trial testing the efficacy of triplet versus doublet chemotherapy regarding clinical complete response and disease-free survival in patients with locally advanced rectal cancer. BMC Cancer. 2024 Jul 26;24(1):901. doi: 10.1186/s12885-024-12529-7. PubMed PMID: 39060961; PubMed Central PMCID: PMC11282593.
Cicali EJ, Eddy E, Gong Y, Elchynski AL, Pena Del Aguila K, Basha T, Daily KC, Dickson L, Fischer S, Hastings-Monari E, Jones D Jr, Ramnaraign BH, DeRemer DL, George TJ, Cooper-DeHoff RM. Implementation of a pharmacogenetic panel-based test for pharmacotherapy-based supportive care in an adult oncology clinic. Clin Transl Sci. 2024 Jul;17(7):e13890. doi: 10.1111/cts.13890. PubMed PMID: 39046302; PubMed Central PMCID: PMC11267631.
Umaretiya PJ, Naranjo A, Zhang FF, Irwin MS, DuBois SG, Bagatell R, Bona K. Enrollment on upfront high-risk neuroblastoma trials by race, ethnicity, and poverty status: A report from the Children’s Oncology Group. Pediatr Blood Cancer. 2024 Jul;71(7):e31051. doi: 10.1002/pbc.31051. Epub 2024 May 5. PubMed PMID: 38706187; PubMed Central PMCID: PMC11116035.
Shoag J, Li Y, Getz KD, Huang YS, Hall M, Naranjo A, Richardson T, Desai AV, Umaretiya PJ, Aziz-Bose R, Kelly CA, Zheng DJ, Newman H, Zahler S, Aplenc R, Bagatell R, Bona K. Healthcare utilization disparities among children with high-risk neuroblastoma treated on Children’s Oncology Group clinical trials. Pediatr Blood Cancer. 2024 Jul 12:e31192. doi: 10.1002/pbc.31192. Online ahead of print. PubMed PMID: 38997807.
Espinoza AF, Bagatell R, McHugh K, Naranjo AH, Van Ryn C, Rojas Y, Lyons K, Guillerman RP, Kirby C, Brock P, Volchenboum S, Simon T, States L, Miller A, Krug B, Sarnacki S, Irtan S, Brisse HJ, Valteau-Couanet D, von Schweinitz D, Kammer B, Granata C, Pio L, Park JR, Nuchtern JG. A subset of image-defined risk factors predict completeness of resection in children with high-risk neuroblastoma: An international multicenter study. Pediatr Blood Cancer. 2024 Jul 28:e31218. doi: 10.1002/pbc.31218. Online ahead of print. PubMed PMID: 39072986.
Bhullar PK, Motaparthi K, Zieman DP, Johnson C, Gurnani P, Sokumbi O. Toxic epidermal necrolysis-like cutaneous toxicity following chimeric antigen receptor T-cell therapy in recurrent large B-cell lymphoma. J Cutan Pathol. 2024 Jul 9. doi: 10.1111/cup.14687. Online ahead of print. PubMed PMID: 38982730.
Chatzkel J, Fishman M, Ramnaraign B, O’Malley P, Sonpavde GP. Approaches to Treating High Risk and Advanced Renal Cell Carcinoma (RCC): Key Trial Data That Impacts Treatment Decisions in the Clinic. Res Rep Urol. 2024 Jul 22;16:161-176. doi: 10.2147/RRU.S457287. eCollection 2024. PubMed PMID: 39072353; PubMed Central PMCID: PMC11282163.
Immuno-Oncology and Microbiome
von Roemeling CA, Patel JA, Carpenter SL, Yegorov O, Yang C, Bhatia A, Doonan BP, Russell R, Trivedi VS, Klippel K, Ryu DH, Grippin A, Futch HS, Ran Y, Hoang-Minh LB, Weidert FL, Golde TE, Mitchell DA. Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade. Nat Commun. 2024 Jul 12;15(1):5871. doi: 10.1038/s41467-024-49989-1. PubMed PMID: 38997283; PubMed Central PMCID: PMC11245621.
Chatzkel J, Fishman M, Ramnaraign B, O’Malley P, Sonpavde GP. Approaches to Treating High Risk and Advanced Renal Cell Carcinoma (RCC): Key Trial Data That Impacts Treatment Decisions in the Clinic. Res Rep Urol. 2024 Jul 22;16:161-176. doi: 10.2147/RRU.S457287. eCollection 2024. PubMed PMID: 39072353; PubMed Central PMCID: PMC11282163.
Kamel AY, Johnson ZD, Hernandez I, Nguyen C, Rolfe M, Joseph T, Dixit D, Shen S, Chaudhry N, Pham A, Rampertab SD, Zimmermann E. Micronutrient deficiencies in inflammatory bowel disease: an incidence analysis. Eur J Gastroenterol Hepatol. 2024 Jul 16. doi: 10.1097/MEG.0000000000002821. Online ahead of print. PubMed PMID: 39012640.
Dupere-Richer D, Riva A, Barwick BG, Maji S, Casellas Roman H, Li J, De U, Sobh A, Quickstad G, Piper C, Kulis M, Ezponda T, Martin-Subero JI, Tonon G, Zhang W, Mitsiades CS, Boise LH, Bennett RL, Licht JD. KDM6A Regulates Immune Response Genes in Multiple Myeloma. Blood. 2024 Jul 24:blood.2024024518. doi: 10.1182/blood.2024024518. Online ahead of print. PubMed PMID: 39046770.
Figg J, Chen D, Falceto Font L, Flores C, Jin D. In Vivo Mouse Models for Adult Brain Tumors: Exploring Tumorigenesis and Advancing Immunotherapy Development. Neuro Oncol. 2024 Jul 11:noae131. doi: 10.1093/neuonc/noae131. Online ahead of print. PubMed PMID: 38990913.
Johnson H, Singh A, Raza A, Sha CM, Wang J, Gowda K, Shen Z, Nair H, Li C, Dokholyan NV, Narayan S, Sharma AK. Identification of a Novel Protein Phosphatase 2A Activator, PPA24, as a Potential Therapeutic for FOLFOX-Resistant Colorectal Cancer. J Med Chem. 2024 Jul 14. doi: 10.1021/acs.jmedchem.4c01077. Online ahead of print. PubMed PMID: 39004939.
Cicali EJ, Eddy E, Gong Y, Elchynski AL, Pena Del Aguila K, Basha T, Daily KC, Dickson L, Fischer S, Hastings-Monari E, Jones D Jr, Ramnaraign BH, DeRemer DL, George TJ, Cooper-DeHoff RM. Implementation of a pharmacogenetic panel-based test for pharmacotherapy-based supportive care in an adult oncology clinic. Clin Transl Sci. 2024 Jul;17(7):e13890. doi: 10.1111/cts.13890. PubMed PMID: 39046302; PubMed Central PMCID: PMC11267631.
Dixit D, Ruiz NC, Shen S, Daneshmand A, Rodriguez VI, Qian S, Neal D, Rampertab SD, Zimmermann EM, Kamel AY. Mucosal Healing among Black and White Patients with Inflammatory Bowel Disease. Clin Transl Gastroenterol. 2024 Jul 15. doi: 10.14309/ctg.0000000000000737. Online ahead of print. PubMed PMID: 39007493.
Mechanisms of Oncogenesis
Dupere-Richer D, Riva A, Barwick BG, Maji S, Casellas Roman H, Li J, De U, Sobh A, Quickstad G, Piper C, Kulis M, Ezponda T, Martin-Subero JI, Tonon G, Zhang W, Mitsiades CS, Boise LH, Bennett RL, Licht JD. KDM6A Regulates Immune Response Genes in Multiple Myeloma. Blood. 2024 Jul 24:blood.2024024518. doi: 10.1182/blood.2024024518. Online ahead of print. PubMed PMID: 39046770.
Qian Z, Yu F. GADD45A: a key tumor suppressor in AML subtypes. Blood. 2024 Jul 4;144(1):6-7. doi: 10.1182/blood.2024024685. No abstract available. PubMed PMID: 38963670.
Zhao T, Hong Y, Yan B, Huang S, Ming GL, Song H. Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a. Nat Commun. 2024 Jul 6;15(1):5674. doi: 10.1038/s41467-024-50010-y. PubMed PMID: 38971831; PubMed Central PMCID: PMC11227589.
Nie DY, Tabor JR, Li J, Kutera M, St-Germain J, Hanley RP, Wolf E, Paulakonis E, Kenney TMG, Duan S, Shrestha S, Owens DDG, Maitland MER, Pon A, Szewczyk M, Lamberto AJ, Menes M, Li F, Penn LZ, Barsyte-Lovejoy D, Brown NG, Barsotti AM, Stamford AW, Collins JL, Wilson DJ, Raught B, Licht JD, James LI, Arrowsmith CH. Recruitment of FBXO22 for targeted degradation of NSD2. Nat Chem Biol. 2024 Jul 4. doi: 10.1038/s41589-024-01660-y. Online ahead of print. PubMed PMID: 38965384.
Li X, Gao L, Wang B, Hu J, Yu Y, Gu B, Xiang L, Li X, Li H, Zhang T, Wang Y, Ma C, Dong J, Lu J, Lucas A, Chen H. FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription. J Immunother Cancer. 2024 Jul 25;12(7):e009565. doi: 10.1136/jitc-2024-009565. PubMed PMID: 39060025; PubMed Central PMCID: PMC11284825.
Xiao Y, Yuan Y, Liu Y, Lin Z, Zheng G, Zhou D, Lv D. Targeted Protein Degradation: Current and Emerging Approaches for E3 Ligase Deconvolution. J Med Chem. 2024 Jul 25;67(14):11580-11596. doi: 10.1021/acs.jmedchem.4c00723. Epub 2024 Jul 9. PubMed PMID: 38981094.
Xiao Y, Awasthee N, Liu Y, Meng C, He MY, Hale S, Karki R, Lin Z, Mosterio M, Garcia BA, Kridel R, Liao D, Zheng G. Discovery of a Highly Potent and Selective HDAC8 Degrader: Advancing the Functional Understanding and Therapeutic Potential of HDAC8. J Med Chem. 2024 Jul 1. doi: 10.1021/acs.jmedchem.4c00761. Online ahead of print. PubMed PMID: 38949959.
Johnson H, Singh A, Raza A, Sha CM, Wang J, Gowda K, Shen Z, Nair H, Li C, Dokholyan NV, Narayan S, Sharma AK. Identification of a Novel Protein Phosphatase 2A Activator, PPA24, as a Potential Therapeutic for FOLFOX-Resistant Colorectal Cancer. J Med Chem. 2024 Jul 14. doi: 10.1021/acs.jmedchem.4c01077. Online ahead of print. PubMed PMID: 39004939.
Brown ME, Thirawatananond P, Peters LD, Kern EJ, Vijay S, Sachs LK, Posgai AL, Brusko MA, Shapiro MR, Mathews CE, Bacher R, Brusko TM. Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function. bioRxiv [Preprint]. 2024 Jul 19:2024.07.16.603756. doi: 10.1101/2024.07.16.603756. PubMed PMID: 39071293; PubMed Central PMCID: PMC11275941.
Nguyen LT, Rakestraw NR, Pizzano BLM, Young CB, Huang Y, Beerensson KT, Fang A, Antal SG, Anamisis KV, Peggs CMD, Yan J, Jing Y, Burdine RD, Adamson B, Toettcher JE, Myhrvold C, Jain PK. Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing. bioRxiv [Preprint]. 2024 Jul 10:2024.07.09.602710. doi: 10.1101/2024.07.09.602710. PubMed PMID: 39026836; PubMed Central PMCID: PMC11257564.