Cancer Control and Population Sciences
Silva RF, Zanon M, Ackman JB, Forte GC, Altmayer S, Biederer J, Bergmann LL, Andrade RGF, Hochhegger B. Comparison of the diagnostic performance of non-contrast MR angiography and planar V/Q scintigraphy for pulmonary embolism: a systematic review and meta-analysis. Eur Radiol. 2025 Jan 26. doi: 10.1007/s00330-025-11366-x. Online ahead of print. PubMed PMID: 39863727.
Yang S, Huang Y, Lou X, Lyu T, Wei R, Mehta HJ, Wu Y, Alvarado M, Salloum RG, Braithwaite D, Huo J, Shih YT, Guo Y, Bian J. Toward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records. JCO Clin Cancer Inform. 2025 Jan;9:e2400139. doi: 10.1200/CCI.24.00139. Epub 2025 Jan 16. PubMed PMID: 39818952; PubMed Central PMCID: PMC11748906.
Yu X, Qin F, Liu S, Brown NJ, Lu Q, Cai G, Guler JL, Xiao F. HapCNV: A Comprehensive Framework for CNV Detection in Low-input DNA Sequencing Data. bioRxiv [Preprint]. 2025 Jan 7:2024.12.19.629494. doi: 10.1101/2024.12.19.629494. PubMed PMID: 39763944; PubMed Central PMCID: PMC11702719.
Brito JP, Herrin J, Swarna KS, Singh Ospina NM, Montori VM, Toro-Tobon D, Umpierrez GE, Galindo RJ, Deng Y, Mickelson MM, Shao H, Polley EC, McCoy RG. GLP-1RA Use and Thyroid Cancer Risk. JAMA Otolaryngol Head Neck Surg. 2025 Jan 23. doi: 10.1001/jamaoto.2024.4852. Online ahead of print. PubMed PMID: 39847346.
Toro-Tobon D, Singh Ospina N, Brito JP. Thyroid Cancer Risk with GLP-1 Receptor Agonists: Evidence, Knowledge Gaps, and the Path Forward. Thyroid. 2025 Jan;35(1):3-5. doi: 10.1089/thy.2024.0690. Epub 2025 Jan 8. No abstract available. PubMed PMID: 39772719.
Beetler DJ, Giresi P, Di Florio DN, Fliess JJ, McCabe EJ, Watkins MM, Xu V, Auda ME, Bruno KA, Whelan ER, Kocsis SPC, Edenfield BH, Walker SA, Macomb LP, Keegan KC, Jain A, Morales-Lara AC, Chekuri I, Hill AR, Farres H, Wolfram J, Behfar A, Stalboerger PG, Terzic A, Cooper LT Jr, Fairweather D. Therapeutic effects of platelet-derived extracellular vesicles on viral myocarditis correlate with biomolecular content. Front Immunol. 2025 Jan 6;15:1468969. doi: 10.3389/fimmu.2024.1468969. eCollection 2024. PubMed PMID: 39835120; PubMed Central PMCID: PMC11743460.
Liang CJ, Luo C, Kranzler HR, Bian J, Chen Y. Communication-efficient federated learning of temporal effects on opioid use disorder with data from distributed research networks. J Am Med Inform Assoc. 2025 Jan 26:ocae313. doi: 10.1093/jamia/ocae313. Online ahead of print. PubMed PMID: 39864407.
Baskir R, Lee M, McMaster SJ, Lee J, Blackburne-Proctor F, Azuine R, Mack N, Schully SD, Mendoza M, Sanchez J, Crosby Y, Zumba E, Hahn M, Aspaas N, Elmi A, Alerte S, Stewart E, Wilfong D, Doherty M, Farrell MM, Hebert GB, Hood S, Thomas CM, Murray DD, Lee B, Stark LA, Lewis MA, Uhrig JD, Bartlett LR, Rico EG, Falcon A, Cohn E, Lunn MR, Obedin-Maliver J, Cottler L, Eder M, Randal FT, Karnes J, Lemieux K, Lemieux N Jr, Lemieux N 3rd, Bradley L, Tepp R, Wilson M, Rodriguez M, Lunt C, Watson K. Research for all: building a diverse researcher community for the All of Us Research Program. J Am Med Inform Assoc. 2025 Jan 1;32(1):38-50. doi: 10.1093/jamia/ocae270. PubMed PMID: 39545358; PubMed Central PMCID: PMC11648709.
Park J, Guo S, Liang M, Zhong X. Investigation of the causal relationship between patient portal utilization and patient’s self-care self-efficacy and satisfaction in care among patients with cancer. BMC Med Inform Decis Mak. 2025 Jan 8;25(1):12. doi: 10.1186/s12911-024-02837-0. PubMed PMID: 39780146; PubMed Central PMCID: PMC11716468. Marchiori E, Hochhegger B, Zanetti G. Rasmussen’s aneurysm. J Bras Pneumol. 2025 Jan 13;50(6):e20240286. doi: 10.36416/1806-3756/e20240286. No abstract available. PubMed PMID: 39813500; PubMed Central PMCID: PMC11665286.
Li F, Sun Z, Abdelhameed A, Duan T, Rasmy L, Hu X, He J, Dang Y, Feng J, Li J, Wang Y, Lyu T, Braun N, Pham S, Gharacholou M, Fairweather D, Zhi D, Bian J, Tao C. Contrastive learning with transformer for adverse endpoint prediction in patients on DAPT post-coronary stent implantation. Front Cardiovasc Med. 2025 Jan 13;11:1460354. doi: 10.3389/fcvm.2024.1460354. eCollection 2024. PubMed PMID: 39872877; PubMed Central PMCID: PMC11769931.
Santiago-Torres M, Mull KE, Sullivan BM, Cupertino AP, Salloum RG, Triplette M, Zvolensky MJ, Bricker JB. Evaluating the Impact of Pharmacotherapy in Augmenting Quit Rates Among Hispanic Adults in an App-Delivered Smoking Cessation Intervention: Secondary Analysis of a Randomized Controlled Trial. JMIR Form Res. 2025 Jan 31;9:e69311. doi: 10.2196/69311. PubMed PMID: 39889280.
Sullivan DR, Golden SE, Schweiger L, Melzer AC, Datta S, Davis JM, Wiener RS, Slatore CG. Associations of Concordant and Shared Lung Cancer Screening Decision Making with Decisional Conflict: A Multi-Institution Cross-Sectional Analysis. MDM Policy Pract. 2025 Jan 17;10(1):23814683241309945. doi: 10.1177/23814683241309945. eCollection 2025 Jan-Jun. PubMed PMID: 39839686; PubMed Central PMCID: PMC11748413.
Mota ME, Alves FA, Jaguar GC, Migliorati CA, Martins MD, Schroter GT, Pinto CA, Moreira MS. Invasive cervical root resorption in a cancer patient: A rare case report with 2 years of follow-up and literature review. Spec Care Dentist. 2025 Jan-Feb;45(1):e13095. doi: 10.1111/scd.13095. PubMed PMID: 39707926.
Cancer Targeting and Therapeutics
Mahadik JD, Assarzadegan N. Connecting the dots: Low-grade appendiceal mucinous neoplasms and serrated polyps in the appendix. Am J Clin Pathol. 2025 Jan 20:aqae183. doi: 10.1093/ajcp/aqae183. Online ahead of print. PubMed PMID: 39832259.
Yu X, Qin F, Liu S, Brown NJ, Lu Q, Cai G, Guler JL, Xiao F. HapCNV: A Comprehensive Framework for CNV Detection in Low-input DNA Sequencing Data. bioRxiv [Preprint]. 2025 Jan 7:2024.12.19.629494. doi: 10.1101/2024.12.19.629494. PubMed PMID: 39763944; PubMed Central PMCID: PMC11702719.
Cavallari LH, Hicks JK, Patel JN, Elchynski AL, Smith DM, Bargal SA, Fleck A, Aquilante CL, Killam SR, Lemke L, Ochi T, Ramsey LB, Haidar CE, Ho T, El Rouby N, Monte AA, Allen JD, Beitelshees AL, Bishop JR, Bousman C, Campbell R, Cicali EJ, Cook KJ, Duong B, Tsermpini EE, Girdwood ST, Gregornik DB, Grimsrud KN, Lamb N, Lee JC, Lopez RO, Mazhindu TA, Morris SA, Nagy M, Nguyen J, Pasternak AL, Petry N, van Schaik RHN, Schultz A, Skaar TC, Al Alshaykh H, Stevenson JM, Stone RM, Tran NK, Tuteja S, Woodahl EL, Yuan LC, Lee CR. The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation. Pharmacogenet Genomics. 2025 Jan 1;35(1):1-11. doi: 10.1097/FPC.0000000000000547. Epub 2024 Oct 3. PubMed PMID: 39485373; PubMed Central PMCID: PMC11664750.
Yang Y, Jn-Simon N, He Y, Sun C, Zhang P, Hu W, Tian T, Zeng H, Basha S, Huerta AS, Sun LZ, Yin XM, Hromas R, Zheng G, Pi L, Zhou D. A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice. Nat Aging. 2025 Jan 31. doi: 10.1038/s43587-025-00811-7. Online ahead of print. PubMed PMID: 39890936.
Ku G, Haag GM, Park H, Lam VK, George TJ, Kim SS, Gutierrez M, Shankaran V, Stein S, Denlinger CS, Elimova E, Nagrial A, He AR, Sawyer MB, Yoon HH, Geva R, Starr J, Curigliano G, Golan T, von Moos R, Fritsch R, Lim D, Wang Q, Patel A, Aoyama T, Lei M, Greenawalt D, Di Bartolomeo M. Nivolumab combination therapies in patients with advanced gastric and gastroesophageal junction cancer: the phase II FRACTION gastric cancer study. ESMO Open. 2025 Jan 10;10(2):104107. doi: 10.1016/j.esmoop.2024.104107. Online ahead of print. PubMed PMID: 39798422; PubMed Central PMCID: PMC11772135.
Chhabra AM, Amos RA, Simone CB 2nd, Kaiser A, Perles LA, Giap H, Hallemeier CL, Johnson JE, Lin H, Wroe AJ, Diffenderfer ES, Wolfgang JA, Sakurai H, Lu HM, Hong TS, Koay EJ, Terashima K, Vitek P, Rule WG, Apisarnthanarax SJ, Badiyan SN, Molitoris JK, Chuong M, Nichols RC Jr. Proton Beam Therapy for Pancreatic Tumors: A Consensus Statement from the Particle Therapy Cooperative Group Gastrointestinal Subcommittee. Int J Radiat Oncol Biol Phys. 2025 Jan 5:S0360-3016(24)03769-6. doi: 10.1016/j.ijrobp.2024.12.020. Online ahead of print. PubMed PMID: 39761799.
Morfouace M, Schoot RA, Hol MLF, Minard-Colin V, Kolb F, Bolle S, Kayembe MT, Gaze MN, Sandler E, Knops RRG, Merks JHM, Smeele LE, Indelicato DJ, Slater O, van Santen HM. Endocrine dysfunction in long-term survivors of pediatric head and neck rhabdomyosarcoma. Eur J Endocrinol. 2025 Jan 6;192(1):25-33. doi: 10.1093/ejendo/lvae168. PubMed PMID: 39775705.
St Thomas N, Christopher BN, Reyes L, Robinson RM, Golick L, Zhu X, Chapman E, Dolloff NG. Pharmacological Modulation of the Unfolded Protein Response as a Therapeutic Approach in Cutaneous T-Cell Lymphoma. Biomolecules. 2025 Jan 7;15(1):76. doi: 10.3390/biom15010076. PubMed PMID: 39858470; PubMed Central PMCID: PMC11763779.
Yang S, Huang Y, Lou X, Lyu T, Wei R, Mehta HJ, Wu Y, Alvarado M, Salloum RG, Braithwaite D, Huo J, Shih YT, Guo Y, Bian J. Toward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records. JCO Clin Cancer Inform. 2025 Jan;9:e2400139. doi: 10.1200/CCI.24.00139. Epub 2025 Jan 16. PubMed PMID: 39818952; PubMed Central PMCID: PMC11748906.
Sharma N, Otsuka Y, Scampavia L, Spicer T, French JB. A high throughput assay for phosphoribosylformylglycinamidine synthase. SLAS Discov. 2025 Jan 15:100212. doi: 10.1016/j.slasd.2025.100212. Online ahead of print. PubMed PMID: 39824442.
Voeller J, Katzenstein HM, Naranjo A, Tenney SC, Chen L, London WB, Handler MH, Schmidt ML, Shimada H, Hogarty MD, Gastier-Foster J, Park JR, Cohn SL, Maris JM, Bagatell R, Twist CJ. Outcomes of patients with intermediate-risk neuroblastoma presenting with motor deficits relating to intraspinal tumor extension: A report from the Children’s Oncology Group study ANBL0531. Pediatr Blood Cancer. 2025 Jan;72(1):e31407. doi: 10.1002/pbc.31407. Epub 2024 Nov 6. PubMed PMID: 39502014; PubMed Central PMCID: PMC11792557.
Raleigh JS, Culp WTN, Giuffrida MA, Thomson C, Martin T, Mathews KG, Skinner O, Leonardi A, Bertran J Selmic LE, Dornbusch J, Wilson J, Oblak M, Fransson B, Lux CN, Wustefeld-Janssens B, Hollenbeck D, Liptak JM, Phillips H, Selting KA, Park JE, Wallace M, Steffey MA, Balsa IM, Mayhew PD, Rebhun RB, Kent MS. Outcomes associated with local treatment of nasal planum squamous cell carcinoma in dogs: 89 cases (2003-2020). J Am Vet Med Assoc. 2025 Jan 10:1-8. doi: 10.2460/javma.24.10.0642. Online ahead of print. PubMed PMID: 39793196.
Immuno-Oncology and Microbiome
Chuck J, Solt LA. SNIPR alert! Making T cells more precise killers. Sci Immunol. 2025 Jan 3;10(103):eadv4911. doi: 10.1126/sciimmunol.adv4911. Epub 2025 Jan 3. PubMed PMID: 39752536.
Shen Z, Seabra G, Brant J, Shirlekar K, Deleyrolle L, Lewis B, Li C. Discovery of PRMT5 N-Terminal TIM Barrel Ligands from Machine-Learning-Based Virtual Screening. ACS Omega. 2025 Jan 2;10(1):1156-1163. doi: 10.1021/acsomega.4c08661. eCollection 2025 Jan 14. PubMed PMID: 39829491; PubMed Central PMCID: PMC11740121.
Chung MC, Mendez-Gomez HR, Soni D, McGinley R, Zacharia A, Ashbrook J, Stover B, Grippin AJ, Sayour EJ, Guan J. Multi-Step Assembly of an RNA-Liposome Nanoparticle Formulation Revealed by Real-Time, Single-Particle Quantitative Imaging. Adv Sci (Weinh). 2025 Jan 31:e2414305. doi: 10.1002/advs.202414305. Online ahead of print. PubMed PMID: 39887619.
Steineck A, Chao K, Hall AG, Jacoby E, Leahy AB, Ligon JA, Luciani K, Schultz LM, Summers CN, Ward L, Winestone LE, Shah NN. Access to CARe: A Narrative of Real-World Medical Decision-Making to Access Chimeric Antigen Receptor (CAR) T-Cell Therapy in Children, Adolescents, and Young Adults. Pediatr Blood Cancer. 2025 Jan 23:e31516. doi: 10.1002/pbc.31516. Online ahead of print. PubMed PMID: 39844726.
Mechanisms of Oncogenesis
Ramalingam P, Gutkin MC, Poulos MG, Winiarski A, Smith A, Carter C, Doughty C, Tillery T, Redmond D, Freire AG, Butler JM. Suppression of thrombospondin-1-mediated inflammaging prolongs hematopoietic health span. Sci Immunol. 2025 Jan 3;10(103):eads1556. doi: 10.1126/sciimmunol.ads1556. Epub 2025 Jan 3. PubMed PMID: 39752538.
Shen Z, Seabra G, Brant J, Shirlekar K, Deleyrolle L, Lewis B, Li C. Discovery of PRMT5 N-Terminal TIM Barrel Ligands from Machine-Learning-Based Virtual Screening. ACS Omega. 2025 Jan 2;10(1):1156-1163. doi: 10.1021/acsomega.4c08661. eCollection 2025 Jan 14. PubMed PMID: 39829491; PubMed Central PMCID: PMC11740121.
Yang Y, Jn-Simon N, He Y, Sun C, Zhang P, Hu W, Tian T, Zeng H, Basha S, Huerta AS, Sun LZ, Yin XM, Hromas R, Zheng G, Pi L, Zhou D. A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice. Nat Aging. 2025 Jan 31. doi: 10.1038/s43587-025-00811-7. Online ahead of print. PubMed PMID: 39890936.
D’Aiuto L, Caldwell JK, Edwards TG, Zhou C, McDonald ML, Di Maio R, Joel WA, Hyde VR, Wallace CT, Watkins SC, Wesesky MA, Shemesh OA, Nimgaonkar VL, Bloom DC. Phosphorylated-tau associates with HSV-1 chromatin and correlates with nuclear speckles decondensation in low-density host chromatin regions. Neurobiol Dis. 2025 Jan 14;206:106804. doi: 10.1016/j.nbd.2025.106804. Online ahead of print. PubMed PMID: 39818277.
Conflitti P, Lyman E, Sansom MSP, Hildebrand PW, Gutierrez-de-Teran H, Carloni P, Ansell TB, Yuan S, Barth P, Robinson AS, Tate CG, Gloriam D, Grzesiek S, Eddy MT, Prosser S, Limongelli V. Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery. Nat Rev Drug Discov. 2025 Jan 2. doi: 10.1038/s41573-024-01083-3. Online ahead of print. PubMed PMID: 39747671.
Poisa-Beiro L, Landry JJM, Yan B, Kardorff M, Eckstein V, Villacorta L, Krammer PH, Zaugg J, Gavin AC, Benes V, Zhou D, Raffel S, Ho AD. A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy. Int J Mol Sci. 2025 Jan 17;26(2):787. doi: 10.3390/ijms26020787. PubMed PMID: 39859500; PubMed Central PMCID: PMC11766015.
Budhkar A, Song Q, Su J, Zhang X. Demystifying the black box: A survey on explainable artificial intelligence (XAI) in bioinformatics. Comput Struct Biotechnol J. 2025 Jan 10;27:346-359. doi: 10.1016/j.csbj.2024.12.027. eCollection 2025. PubMed PMID: 39897059; PubMed Central PMCID: PMC11782883.