Cancer Control and Population Sciences
Mullis MD, Bylund CL, Bagautdinova D, Bryan EG, Sae-Hau M, Weiss ES, Lagmay JP, Fisher CL. “Somewhat of an Adult”: Understanding the “Dance” of Competing Tensions Parents Manage While Caring for an Adolescent or Young Adult (AYA) Diagnosed with Hematologic Malignancy. Cancers (Basel). 2025 Apr 12;17(8):1299. doi: 10.3390/cancers17081299. PubMed PMID: 40282475; PubMed Central PMCID: PMC12026285.
Hong YR, Wang R, Carrier A, Ricks-Santi L, Kea T, Patel K, Virnig BA, Sahin I, Braithwaite D. Association between cancer screenings uptake and genetic testing for cancer risk among US adults: findings from HINTS 2017-2020. J Community Genet. 2025 Apr 30. doi: 10.1007/s12687-025-00797-0. Online ahead of print. PubMed PMID: 40304964.
Yaghjyan L, Heng YJ, Sardella BR, Murthy D, Mahoney MB, Rosner B, Polyak K, Ratcliff M, Tamimi RM. Associations of circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 with the expression of stem cell markers in benign breast tissue. Breast Cancer Res. 2025 Apr 7;27(1):53. doi: 10.1186/s13058-025-02002-z. PubMed PMID: 40197284; PubMed Central PMCID: PMC11978140.
Burin M, Lopez J, Sattari M. Not Everything That Shines Is Gold: Reactive Lymphadenopathy After COVID-19 Vaccination in a Breast Cancer Survivor. J Gen Intern Med. 2025 Apr 10. doi: 10.1007/s11606-025-09484-9. Online ahead of print. No abstract available. PubMed PMID: 40210801.
Balaguru L, Benites C, Hanubal KS, Liu G, Lee JH, Conrad D, White C, Vijay A, Dziegielewski PT. The predictive value of tumor depth of invasion for contralateral neck disease in tongue cancer. Oral Oncol. 2025 Apr 26;165:107334. doi: 10.1016/j.oraloncology.2025.107334. Online ahead of print. PubMed PMID: 40288076.
Dalisay F, Hong YR, Chu H, Salloum RG. Factors associated with smoking and e-cigarette use statuses among individuals with chronic diseases after hurricanes Helene and Milton. Tob Induc Dis. 2025 Apr 30;23. doi: 10.18332/tid/203427. eCollection 2025. PubMed PMID: 40309025; PubMed Central PMCID: PMC12042274.
Murray JD, Leong MC, Sylvester S, Ashby W, Manhan A, Cortese R, Marcelli A, Lou XY, Crawford KM, Celso BG, Lee JH. Nipple Sensation After Superomedial Breast Reduction: A Single Surgeon Study Evaluating Prognostic Factors. Plast Reconstr Surg Glob Open. 2025 Apr 16;13(4):e6707. doi: 10.1097/GOX.0000000000006707. eCollection 2025 Apr. PubMed PMID: 40242725; PubMed Central PMCID: PMC12002371.
LeLaurin JH, Montague M, Curtis ME, Salloum RG, Sheikh S, Hendry PL. Implementation of a novel pain coach educator program in a safety-net emergency department. Implement Res Pract. 2025 Apr 4;6:26334895251330511. doi: 10.1177/26334895251330511. eCollection 2025 Jan-Dec. PubMed PMID: 40191386; PubMed Central PMCID: PMC11970099.
Smith-Bindman R, Chu PW, Azman Firdaus H, Stewart C, Malekhedayat M, Alber S, Bolch WE, Mahendra M, Berrington de Gonzalez A, Miglioretti DL. Projected Lifetime Cancer Risks From Current Computed Tomography Imaging. JAMA Intern Med. 2025 Apr 14:e250505. doi: 10.1001/jamainternmed.2025.0505. Online ahead of print. PubMed PMID: 40227719; PubMed Central PMCID: PMC11997853.
D’Lugos AC, Ducharme JB, Callaway CS, Trevino JG, Atkinson C, Judge SM, Judge AR. Complement pathway activation mediates pancreatic cancer-induced muscle wasting and pathological remodeling. J Clin Invest. 2025 Apr 8:e178806. doi: 10.1172/JCI178806. Online ahead of print. PubMed PMID: 40198138.
Beekman C, Carrasco-Rojas N, Withrow J, Dawson R, Bolch WE, Paganetti H. Radiation-induced lymphopenia: In-silico replications of preclinical studies suggest importance of dose to lymphoid organs. Int J Radiat Oncol Biol Phys. 2025 Apr 14:S0360-3016(25)00358-X. doi: 10.1016/j.ijrobp.2025.03.080. Online ahead of print. PubMed PMID: 40239822.
Shin B, Kim S, Choi C, Kim H, Yeom YS, Chung BS, Nguyen TT, Bolch WE, Moon S, Han H, Kim CH. ICRP pregnant-female mesh-type reference computational phantoms part 2: development of maternal phantoms. Phys Med Biol. 2025 Apr 24. doi: 10.1088/1361-6560/add07a. Online ahead of print. PubMed PMID: 40273940.
Dike CR, Lowe M, Forsmark C, Searle S, Holt J, Abu-El-Haija M. Using Animations to Educate Children and Caregivers on Pediatric Pancreatitis – Assessing the Impact and Utilization of the National Pancreas Foundation’s Pediatric Animated Pancreas Patient. Pancreas. 2025 Apr 2. doi: 10.1097/MPA.0000000000002494. Online ahead of print. PubMed PMID: 40168620.
Boamah Mensah AB, Konney TO, Adankwah E, Amuasi J, Nones M, Okyere J, Boadu KO, Eduah FME, Xiong S, Moon JR, Virnig B, Kulasingam S. Perceptions of barriers and facilitators for cervical cancer screening from women and healthcare workers in Ghana: Applying the Dynamic Sustainability Framework. PLOS Glob Public Health. 2025 Apr 30;5(4):e0003011. doi: 10.1371/journal.pgph.0003011. eCollection 2025. PubMed PMID: 40305464.
Cancer Targeting and Therapeutics
Wen Y, Li Y, Cheng S, Crow J, Samuel G, Vishwakarma V, Turaga SM, Bantis L, Godwin AK, Zeng Y. Partition-Less Digital Immunoassay Using Configurable Topographic Nanoarrays for Extracellular Vesicle Diagnosis of Ewing Sarcoma. ACS Nano. 2025 Apr 1;19(12):11973-11986. doi: 10.1021/acsnano.4c16904. Epub 2025 Mar 21. PubMed PMID: 40115997.
D’Lugos AC, Ducharme JB, Callaway CS, Trevino JG, Atkinson C, Judge SM, Judge AR. Complement pathway activation mediates pancreatic cancer-induced muscle wasting and pathological remodeling. J Clin Invest. 2025 Apr 8:e178806. doi: 10.1172/JCI178806. Online ahead of print. PubMed PMID: 40198138.
Chen M, Dhakal D, Eckhardt CW, Luesch H, Ding Y. Synthetic biology strategies for cyanobacterial systems to heterologously produce cyanobacterial natural products. Nat Prod Rep. 2025 Apr 16. doi: 10.1039/d5np00009b. Online ahead of print. PubMed PMID: 40237791; PubMed Central PMCID: PMC12002140.
Zhang X, Thummuri D, Hu W, Liu X, Zhang P, Zhou S, Zhou D, Zheng G. Discovery of XZ338, a highly potent BCL-XL degrader. Eur J Med Chem. 2025 Apr 15;291:117624. doi: 10.1016/j.ejmech.2025.117624. Online ahead of print. PubMed PMID: 40239483.
Elsadek LA, Seabra G, Paul VJ, Luesch H. Grassystatin G, a new cathepsin D inhibitor from marine cyanobacteria: discovery, synthesis, and biological characterization. RSC Med Chem. 2025 Apr 25. doi: 10.1039/d5md00017c. Online ahead of print. PubMed PMID: 40291136; PubMed Central PMCID: PMC12024474.
Shastri VM, Madabushi SS, Hui SK, Lamba JK. CD33-D2 isoform characterization for advancement of its therapeutic potential. Immunotherapy. 2025 Apr;17(5):347-354. doi: 10.1080/1750743X.2025.2493038. Epub 2025 Apr 24. PubMed PMID: 40272002.
Chan P, Nagai Y, Wu Q, Hovsepyan A, Mkhitaryan S, Wang J, Karapetyan G, Kamenecka T, Solt LA, Cope J, Moats RA, Hirota T, Rich JN, Kay SA. Advancing Clinical Response Against Glioblastoma: Evaluating SHP1705 CRY2 Activator Efficacy in Preclinical Models and Safety in Phase I Trials. Neuro Oncol. 2025 Apr 1:noaf089. doi: 10.1093/neuonc/noaf089. Online ahead of print. PubMed PMID: 40168112.
Gomes FP, Durbin KR, Schauer K, Nwachukwu JC, R Kobylski R, Njeri JW, Seath CP, Saviola AJ, McClatchy DB, Diedrich JK, Garrett PT, Papa AB, Ciolacu I, Kelleher NL, Nettles KW, Yates JR 3rd. Native top-down proteomics enables discovery in endocrine-resistant breast cancer. Nat Chem Biol. 2025 Apr 4. doi: 10.1038/s41589-025-01866-8. Online ahead of print. PubMed PMID: 40186031.
Lin J, He R, Qu Z, Dong J, Krabill AD, Wu L, Bai Y, Conroy LR, Bruntz RC, Miao Y, Jassim BA, Babalola B, Nguele Meke FGB, Sun R, Gentry MS, Zhang ZY. Discovery and Evaluation of Active Site-Directed, Potent, and Selective Sulfophenyl Acetic Amide-Based Inhibitors for the Laforin Phosphatase. J Med Chem. 2025 Apr 16. doi: 10.1021/acs.jmedchem.4c02580. Online ahead of print. PubMed PMID: 40238926.
Mullis MD, Bylund CL, Bagautdinova D, Bryan EG, Sae-Hau M, Weiss ES, Lagmay JP, Fisher CL. “Somewhat of an Adult”: Understanding the “Dance” of Competing Tensions Parents Manage While Caring for an Adolescent or Young Adult (AYA) Diagnosed with Hematologic Malignancy. Cancers (Basel). 2025 Apr 12;17(8):1299. doi: 10.3390/cancers17081299. PubMed PMID: 40282475; PubMed Central PMCID: PMC12026285.
Kollareth DJM, Leroy V, Tu Z, Woolet-Stockton MJ, Kamat M, Garrett TJ, Atkinson C, Cai G, Upchurch GR Jr, Sharma AK. Lipoxin A4/FPR2 Signaling Mitigates Ferroptosis of Alveolar Epithelial Cells via NRF2-Dependent Pathway During Lung Ischemia-Reperfusion Injury. FASEB J. 2025 Apr 30;39(8):e70545. doi: 10.1096/fj.202401475R. PubMed PMID: 40270323.
Serrano A, Louviere C, Singh A, Ozdemir S, Hernandez M, Balaji KC, Gopireddy DR, Gumus KZ. Predicting clinically significant prostate cancer in PI-RADS 3 lesions using MRI-based radiomics: a literature review of methodological variations and performance. Abdom Radiol (NY). 2025 Apr 2. doi: 10.1007/s00261-025-04914-y. Online ahead of print. PubMed PMID: 40172658.
Khamooshi P, Vijayan K, Mehta HJ, DiRico M. Cyanoacrylate glue topical adhesive for bronchoscopic repair of tracheal laceration. BMJ Case Rep. 2025 Apr 26;18(4):e264524. doi: 10.1136/bcr-2024-264524. PubMed PMID: 40287148.
Immuno-Oncology and Microbiome
Hazime H, Ducasa GM, Santander AM, Brito N, Gonzalez-Horta EE, Quintero MA, Barnes S, Wilson L, Zhang Y, Yu F, Gharaibeh RZ, Jobin C, Faust KM, Damas OM, Deshpande A, Kerman DH, Proksell S, Pignac-Kobinger J, Fernandez I, Burgueno JF, Abreu MT. DUOX2 activation drives bacterial translocation and subclinical inflammation in IBD-associated dysbiosis. Gut. 2025 Apr 29:gutjnl-2024-334346. doi: 10.1136/gutjnl-2024-334346. Online ahead of print. PubMed PMID: 40301115.
Chan P, Nagai Y, Wu Q, Hovsepyan A, Mkhitaryan S, Wang J, Karapetyan G, Kamenecka T, Solt LA, Cope J, Moats RA, Hirota T, Rich JN, Kay SA. Advancing Clinical Response Against Glioblastoma: Evaluating SHP1705 CRY2 Activator Efficacy in Preclinical Models and Safety in Phase I Trials. Neuro Oncol. 2025 Apr 1:noaf089. doi: 10.1093/neuonc/noaf089. Online ahead of print. PubMed PMID: 40168112.
Chakraborty AK, Raut RD, Iqbal K, Choudhury C, Alhousami T, Chogle S, Acosta AS, Fagman L, Deabold K, Takada M, Sahay B, Kumar V, Bais MV. Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression. Int J Oral Sci. 2025 Apr 17;17(1):31. doi: 10.1038/s41368-025-00363-x. PubMed PMID: 40246812; PubMed Central PMCID: PMC12006301.
Pearce EM, Evans E, Mayday MY, Reyes G, Simon MR, Blum J, Kim H, Mu J, Shaw PJ, Rowan CM, Auletta JJ, Martin PL, Hurley C, Kreml EM, Qayed M, Abdel-Azim H, Keating AK, Cuvelier GDE, Hume JR, Killinger JS, Godder K, Hanna R, Duncan CN, Quigg TC, Castillo P, Lalefar NR, Fitzgerald JC, Mahadeo KM, Satwani P, Moore TB, Hanisch B, Abdel-Mageed A, Davis DB, Hudspeth MP, Yanik GA, Pulsipher MA, Dvorak CCJL, Zinter MS. Integrating Pulmonary and Systemic Transcriptomic Profiles to Characterize Lung Injury after Pediatric Hematopoietic Stem Cell Transplant. medRxiv [Preprint]. 2025 Apr 1:2025.03.31.25324969. doi: 10.1101/2025.03.31.25324969. PubMed PMID: 40236411; PubMed Central PMCID: PMC11998824.
Mechanisms of Oncogenesis
Lee KM, Castro E, Ratcliffe J, Lerner C, Caglayan M. Nick sealing of polbeta mismatch insertion products by LIG1 and LIG3alpha during 8-oxoG bypass leads to mutagenic or error-free base excision repair. J Biol Chem. 2025 Apr 24:108540. doi: 10.1016/j.jbc.2025.108540. Online ahead of print. PubMed PMID: 40286853.
Caglayan M. Repair pathway coordination from gap filling by polbeta and subsequent nick sealing by LIG1 or LIG3alpha governs BER efficiency at the downstream steps. DNA Repair (Amst). 2025 Apr;148:103826. doi: 10.1016/j.dnarep.2025.103826. Epub 2025 Mar 10. PubMed PMID: 40081282; PubMed Central PMCID: PMC12038979.
Lin J, He R, Qu Z, Dong J, Krabill AD, Wu L, Bai Y, Conroy LR, Bruntz RC, Miao Y, Jassim BA, Babalola B, Nguele Meke FGB, Sun R, Gentry MS, Zhang ZY. Discovery and Evaluation of Active Site-Directed, Potent, and Selective Sulfophenyl Acetic Amide-Based Inhibitors for the Laforin Phosphatase. J Med Chem. 2025 Apr 16. doi: 10.1021/acs.jmedchem.4c02580. Online ahead of print. PubMed PMID: 40238926.
Zhang X, Thummuri D, Hu W, Liu X, Zhang P, Zhou S, Zhou D, Zheng G. Discovery of XZ338, a highly potent BCL-XL degrader. Eur J Med Chem. 2025 Apr 15;291:117624. doi: 10.1016/j.ejmech.2025.117624. Online ahead of print. PubMed PMID: 40239483.
Kollareth DJM, Leroy V, Tu Z, Woolet-Stockton MJ, Kamat M, Garrett TJ, Atkinson C, Cai G, Upchurch GR Jr, Sharma AK. Lipoxin A4/FPR2 Signaling Mitigates Ferroptosis of Alveolar Epithelial Cells via NRF2-Dependent Pathway During Lung Ischemia-Reperfusion Injury. FASEB J. 2025 Apr 30;39(8):e70545. doi: 10.1096/fj.202401475R. PubMed PMID: 40270323.
Yin K, Villareal L, Wu X, Arcos M, Lee J, Martin DR, In JG, Leslie K, Zhang DD, Xue X. STEAP4 Target NQO1 Mediates Colon Tumorigenesis. J Cell Sci. 2025 Apr 10:jcs.263402. doi: 10.1242/jcs.263402. Online ahead of print. PubMed PMID: 40205952.
Labilloy G, Tanaka S, Black LP, Augustin B, Hopson C, Bethencourt J, Wu D, Sulaiman D, Bertrand A, Salomao R, Graim K, Datta S, Reddy S, Guirgis FW, Hofmaenner DA. Identifying a Sepsis Subphenotype Characterized by Dysregulated Lipoprotein Metabolism Using a Simplified Clinical Data Algorithm. Shock. 2025 Apr 23. doi: 10.1097/SHK.0000000000002605. Online ahead of print. PubMed PMID: 40267485.